Low-Volatility Dicarboxylic Diesters for Stable Methane Inhibition

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Solution Overview

Problem

Existing methane-reducing agents for ruminants have high vapor pressures, leading to storage instability and the need for overdosing, which is undesirable.

Innovation Solution

Development of novel dicarboxylic acid diesters with low vapor pressures that effectively inhibit methane production in ruminants, providing enhanced storage stability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If methane-reducing agents with high vapor pressure are used, then methane production is inhibited, but storage stability deteriorates

Engineering Contradiction:
Improvestorage stabilityVSAvoidvapor pressure
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent applies parameter changes by modifying the vapor pressure characteristic of the methane-reducing agent. The diester compounds are specifically designed to have a vapor pressure of less than 0.01 mbar at 20°C, which is a dramatic reduction from conventional agents. This parameter change resolves the contradiction by enabling both effective methane inhibition and long-term storage stability without active ingredient loss.

Inventive Principle:
Principle #35Parameter changes

2Reliability

If methane-reducing agents are used, then methane production is inhibited, but dosing precision deteriorates due to volatility

Engineering Contradiction:
Improvemethane inhibition effectivenessVSAvoiddosing precision
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent changes the vapor pressure parameter to less than 0.01 mbar, which eliminates the volatility problem that causes dosing precision deterioration. The low vapor pressure ensures that the active ingredient remains stable during storage and application, allowing for precise dosing without overdosing to compensate for losses.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If overdosing is applied to compensate for storage instability, then storage stability is improved, but cost and efficiency worsen

Engineering Contradiction:
Improvestorage stabilityVSAvoidcost efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The patent changes the vapor pressure parameter to achieve inherent storage stability without requiring overdosing. The diester compounds with vapor pressure < 0.01 mbar maintain their activity during storage, eliminating the need to add excess active ingredient to compensate for volatility losses, thus improving cost efficiency while maintaining effectiveness.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS12497347B2Dicarboxylic acid diesters
Publication Date: 2025.12.16 DSM IP ASSETS BV
  • US12497347B2 patent drawing
  • US12497347B2 patent drawing
  • US12497347B2 patent drawing

AI summary

Dicarboxylic diesters are disclosed having the formula (I):wherein n is 3, and X is a C2 alkylene or a C2 alkenylene group. Such dicarboxylic diesters are useful for inhibiting the methane production in ruminants.