Diced Acellular Dermal Matrix for Breast Volume Restoration
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Solution Overview
Problem
Breast-conserving surgery often results in asymmetrical breast volume and shape post-operatively, with existing methods like implant insertion or tissue flaps leading to unnatural results and increased costs, and the challenge of filling irregularly shaped cavities after tumor removal remains unsolved.
Innovation Solution
A surgical method using a retromammary approach for breast-conserving surgery, where a diced acellular dermal matrix (dADM) is used to fill the defect after tumor removal, minimizing additional incisions and promoting natural breast contour preservation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If breast-conserving surgery is performed to preserve breast tissue, then the patient avoids mutilating mastectomy, but the immediate breast volume and shape become asymmetrical with the contralateral breast
Solution Approach 1:
The acellular dermal matrix is diced into small particles (1-3mm in diameter) to create a granular filling material that can be evenly distributed throughout the resection cavity, allowing for precise volume replacement and natural contour restoration without large visible incisions
Solution Approach 2:
The diced acellular dermal matrix acts as an intermediary material that integrates with the patient's own breast tissue, providing structural support and volume replacement while maintaining natural breast architecture and avoiding the need for foreign implants or complex flap procedures
2Shape
If implant insertion or tissue flap procedures are used for volume replacement, then breast shape and volume can be restored, but additional long incisions remain and the result appears unnatural
Solution Approach 1:
The diced acellular dermal matrix particles are injected directly into the resection cavity through the existing surgical incision, allowing the filling material to be placed precisely where needed without creating additional incisions, thereby maintaining local tissue quality and natural appearance
Solution Approach 2:
Instead of using large implants or complex flaps that require extensive incisions, the invention inverts the approach by using small diced particles that can be delivered through minimal access, achieving volume replacement through the existing surgical pathway rather than requiring new access points
3Volume of stationary object
If sheet-type ADM is cut and tailored to fit the breast defect, then volume replacement can be achieved, but it is difficult to transform to have a suitable shape for irregular cavities
Solution Approach 1:
The acellular dermal matrix is segmented into small diced particles (1-3mm diameter) that can flow and distribute themselves to conform to any irregular cavity shape, eliminating the need for complex tailoring and customization required by sheet-type ADM
Solution Approach 2:
The physical state of the acellular dermal matrix is changed from a solid sheet form to a granular particulate form, fundamentally altering its ability to adapt to irregular geometries and making it easily injectable through minimal access incisions
Data Source
AI summary
The present invention relates to breast-conserving surgery with volume replacement using dADM for breast cancer.The surgical method according to the present invention is oncologically and cosmetically effective in terms of reducing postoperative fat necrosis, and may easily preserve the volume and shape of the preoperative breast mound. The effective shortening of the surgical time and a significant reduction in intraoperative bleeding may significantly reduce the incidence of postoperative complications such as postoperative intramammary fat necrosis and skin flap necrosis after the occurrence of subcutaneous fat necrosis.