Dietary Supplement Composition for Cholesterol Reduction
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Solution Overview
Problem
Current treatments for elevated cholesterol levels often cause significant side effects, such as liver problems, and there is a need for a dietary supplement that can effectively reduce blood cholesterol levels without these adverse effects.
Innovation Solution
A dietary supplement composition comprising phytosterols, soluble fiber, guggulsterones, policosanol, glucaric acid salts, anthocyanins, CoQ10, phytoestrogens, chromium, pantethine, artichoke leaf extract, and Salvia miltiorrhiza, which are combined to reduce total and LDL cholesterol levels while maintaining or increasing HDL levels, formulated as pills, capsules, or other forms for easy consumption.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If current treatments for elevated cholesterol levels are used, then cholesterol levels are reduced, but significant side effects such as liver problems occur
Solution Approach 1:
The patent uses naturally occurring, short-acting dietary components (phytosterols, soluble fiber, guggulsterones, policosanol, glucaric acid salts, anthocyanins, CoQ10, phytoestrogens, chromium, pantethine, artichoke leaf extract, and Salvia miltiorrhiza) instead of long-term pharmaceutical interventions. These natural substances provide cholesterol-lowering effects without the cumulative liver toxicity associated with conventional drugs, allowing for safer prolonged use through multiple interchangeable natural agents.
Solution Approach 2:
The patent combines multiple natural cholesterol-lowering substances into a composite dietary supplement formulation. This composite approach synergistically enhances cholesterol reduction effectiveness while distributing potential side effects across multiple gentle natural ingredients rather than relying on a single potent pharmaceutical agent, thereby reducing overall hepatotoxicity risk.
2Reliability
If a dietary supplement is designed to effectively reduce cholesterol levels, then cholesterol reduction is achieved, but the complexity of the supplement composition increases
Solution Approach 1:
The patent divides the cholesterol-lowering function into multiple discrete natural ingredient segments, each contributing a specific mechanism (e.g., phytosterols for intestinal cholesterol absorption inhibition, soluble fiber for bile acid binding, guggulsterones for lipid metabolism modulation). This segmentation allows for modular formulation where ingredients can be individually selected and optimized based on their specific cholesterol-lowering mechanisms, making the complex composition more manageable and scientifically rationale.
Solution Approach 2:
The patent selects ingredients that perform multiple functions: for example, soluble fiber not only reduces cholesterol absorption but also promotes gut health and satiety; CoQ10 not only supports heart health but also acts as an antioxidant; artichoke leaf extract provides both cholesterol-lowering and digestive benefits. This multi-functionality justifies the composite formulation by providing additional health benefits beyond cholesterol reduction, making the complexity worthwhile.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The supplement significantly lowers total and LDL cholesterol levels, improves triglycerides, and increases HDL levels, reducing the risk of cardiovascular disease without causing significant side effects, as demonstrated in clinical studies.
Implementation Method 1
Phytosterols inhibit intestinal cholesterol absorption, thereby lowering plasma total and low-density lipoprotein (LDL) cholesterol levels
Implementation Method 2
Soluble fiber has been scientifically proven to reduce blood cholesterol levels
Implementation Method 3
Guggul lipid contains ketonic steroid compounds known as guggulsterones, which have been shown to provide the lipid-lowering actions
Implementation Method 4
policosanol consumption can lower cholesterol, inhibit experimentally induced atherosclerotic lesions of cerebral ischemia, help prevent the peroxidation of lipoproteins
Implementation Method 5
Coenzyme Q 10 (CoQ10) is essential for human life. It catalyzes the formation and utilization of energy in every human cell
Implementation Method 6
Resveratrol is a polyphenolic compound found in the skin of red grapes, which is a powerful phytoestrogen, cardioprotectant, and anti-oxidant
Data Source
AI summary
The disclosure is generally directed to methods and compositions for reducing blood cholesterol levels, and more particularly to dietary supplements for reducing blood cholesterol levels. The dietary supplements for reducing cholesterol typically comprise at least one phytosterol source, at least one soluble fiber source, at least one guggulsterone source, and at least one policosanol source.