Diffusion Gradient Vector Selection for MRI Signal-to-Noise Ratio

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Solution Overview

Problem

Current methods for recording diffusion-weighted magnetic resonance image data struggle with achieving optimal performance, particularly in anisotropic diffusion directions, leading to suboptimal signal-to-noise ratios and limited resolution due to constraints on gradient amplitudes and directional dependencies.

Innovation Solution

A method is introduced that defines a cuboid space of achievable diffusion gradient vectors and selects a set of at least six diffusion gradient vectors meeting specific directional constraints, allowing for higher effective gradient amplitudes and improved signal-to-noise ratios, enabling more precise image acquisition and reduced echo times.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional diffusion gradient scanning sequences are used, then diffusion-weighted magnetic resonance recordings can be obtained, but the signal-to-noise ratio is suboptimal and image resolution is limited due to constraints on gradient amplitudes

Engineering Contradiction:
Improvesignal-to-noise ratioVSAvoidgradient amplitude constraints
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies dynamics by making the gradient vector selection adaptive and variable rather than fixed. The system dynamically selects from multiple possible gradient vectors based on the specific imaging requirements and tissue characteristics, allowing the gradient amplitude and direction to be optimized for each measurement condition rather than being constrained by a single conventional sequence design.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The patent changes the parameters of the diffusion gradient vectors by selecting from multiple possible vectors with different amplitudes and directions. This allows optimization of the effective gradient amplitude to improve signal-to-noise ratio while still satisfying the b-value requirement, thereby resolving the contradiction between measurement precision and device constraints.

Inventive Principle:
Principle #35Parameter changes

2Loss of information

If multiple diffusion directions are recorded to detect anisotropic diffusion, then directional information is obtained, but scanning time increases

Engineering Contradiction:
Improvedirectional informationVSAvoidscanning time
Core Design Contradiction:
Loss of informationVSLoss of time

Solution Approach 1:

The patent applies partial action by selecting a specific subset of diffusion gradient vectors from the complete set of possible vectors. Rather than recording all possible diffusion directions, the system selects only those vectors necessary to achieve the desired tensor determination, thereby reducing scanning time while still obtaining sufficient directional information for anisotropic diffusion detection.

Inventive Principle:
Principle #16Partial or excessive action

Solution Approach 2:

The patent applies preliminary action by pre-calculating and storing multiple possible diffusion gradient vectors that satisfy the directional constraints for tensor determination. This allows the system to quickly select from pre-prepared options during actual scanning, reducing the computational and temporal overhead during the imaging process itself.

Inventive Principle:
Principle #10Preliminary action

3Measurement precision

If higher gradient amplitudes are used to improve signal-to-noise ratio, then image quality increases, but the constraints on maximum gradient amplitudes are violated

Engineering Contradiction:
Improveimage qualityVSAvoidgradient amplitude constraints
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent changes the parameters by selecting gradient vectors with optimized amplitudes that maximize the effective gradient strength while remaining within the maximum amplitude constraints of the gradient system. This allows achieving higher signal-to-noise ratio and better image quality without violating the hardware limitations.

Inventive Principle:
Principle #35Parameter changes

4Manufacturing precision

If conventional gradient vector selection is used, then simple implementation is maintained, but image resolution and signal-to-noise ratio are limited

Engineering Contradiction:
Improveimage resolutionVSAvoidgradient vector selection complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by pre-calculating and storing multiple possible diffusion gradient vectors that satisfy the directional constraints for tensor determination. This allows the system to quickly select from pre-prepared options during actual scanning, reducing the computational and temporal overhead during the imaging process itself.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enhances the signal-to-noise ratio, reduces scanning time, and increases image resolution by optimizing the selection of diffusion gradient vectors, thereby improving the quality and precision of diffusion-weighted magnetic resonance imaging.

Implementation Method 1

the activation of a specific sequence of gradient magnetic field pulses that vary the field strength of the external magnetic field in a prespecified direction

Methodology Applied
Scientific EffectElectromagnetic Induction: Electromagnetic Induction

Implementation Method 2

With a diffusion movement, the precessing nuclear spins move out of phase, and thus can be identified in the measuring signal

Methodology Applied
Scientific EffectMagnetic Field: Magnetic Field

Data Source

PatentUS10495714B2Method and apparatus for recording of diffusion-weighted magnetic resonance image data with anisotropic diffusion directions
Publication Date: 2019.12.03 SIEMENS HEALTHINEERS AG
  • US10495714B2 patent drawing
  • US10495714B2 patent drawing
  • US10495714B2 patent drawing

AI summary

In a method and a magnetic resonance apparatus for diffusion-weighted imaging, diffusion gradients for acquiring diffusion-weighted image data, with anisotropic diffusion directions, are determined by defining a space of achievable diffusion gradient vectors as a cuboid, and then defining a spherical shell around the gradient axes in order to determine specific values of the gradient amplitudes. The resulting diffusion gradient vectors have a direct influence on the achievable signal-to-noise ratio of an individual scan, and the method and apparatus enable an advance selection of a desired effective gradient amplitude, and the presentation to a user of candidate diffusion gradient vectors that satisfy the desired requirements.