Diffusion Kurtosis Imaging Using Unconstrained Tensor Fitting

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Solution Overview

Problem

Existing diffusion kurtosis imaging methods require time-consuming calculations using constrained optimization algorithms, which hinder efficient generation of parameter images.

Innovation Solution

Utilize an unconstrained optimization algorithm to fit scan image signals and determine elements of the diffusion tensor and kurtosis tensor, followed by generating parameter images based on these elements, thereby reducing calculation time.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If constrained optimization algorithms are used to calculate diffusion tensor and kurtosis tensor elements, then the calculation results are reliable, but the calculation time is excessive

Engineering Contradiction:
Improvecalculation reliabilityVSAvoidcalculation time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent changes the optimization algorithm from constrained to unconstrained type, fundamentally altering the computational approach. This parameter change in the algorithm category enables faster convergence and reduces calculation time while maintaining acceptable reliability through alternative constraint handling methods

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent replaces the traditional constrained optimization mechanical system with an unconstrained optimization system. This substitution involves changing the mathematical framework from one with explicit constraints to one that handles constraints implicitly, thereby reducing computational complexity and time

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If constrained optimization algorithms are used to generate parameter images, then the imaging accuracy is maintained, but the generation speed is slow

Engineering Contradiction:
Improveimaging accuracyVSAvoidimage generation speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The patent changes the optimization algorithm parameter from constrained to unconstrained, which fundamentally improves the generation speed. The unconstrained algorithm achieves faster convergence and reduces computational iterations while maintaining imaging accuracy through refined parameter estimation techniques

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent performs preliminary actions by pre-processing the diffusion-weighted images and preparing the data structure before running the unconstrained optimization algorithm. This preliminary preparation reduces the computational burden during the main calculation phase, thereby increasing generation speed without sacrificing accuracy

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12465216B2Diffusion kurtosis imaging method, computer device and storage medium
Publication Date: 2025.11.11 SHANGHAI UNITED IMAGING HEALTHCARE
  • US12465216B2 patent drawing
  • US12465216B2 patent drawing
  • US12465216B2 patent drawing

AI summary

The disclosure provides a diffusion kurtosis imaging method, which includes acquiring scan image signals of a scanned object; fitting the scan image signals using an unconstrained optimization algorithm to obtain elements of a first diffusion tensor and elements of a first kurtosis tensor; determining at least one type of parameters of diffusion tensor imaging parameters or kurtosis tensor imaging parameters based on the elements of the first diffusion tensor and the elements of the first kurtosis tensor; and generating a parameter image based on the at least one type of parameters of diffusion tensor imaging parameters or kurtosis tensor imaging parameters.