Digital Pupillometer Imaging for Precise Shape Irregularity Grading

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Solution Overview

Problem

Existing pupillometers lack the capability for precise detection, measurement, and grading of pupillary shape and irregularities, which are crucial for diagnosing neurological conditions and monitoring visual pathway impairments.

Innovation Solution

Development of a pupillometer equipped with a digital camera, microprocessor, and imaging modalities such as speckle and spectral imaging to analyze pupil shape and iris vasculature, capable of detecting neurological disorders like traumatic brain injury and stroke through vascular changes and biomarker detection.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If traditional pupillometers are used, then basic pupil size measurement is achieved, but precise detection and grading of pupillary shape and irregularities cannot be performed

Engineering Contradiction:
Improvepupillary shape detection precisionVSAvoidpupillometer system complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The pupillary assessment is segmented into multiple independent measurement components: pupil size measurement, shape analysis, irregularity detection, and grading. Each component can be processed separately through the digital camera imaging system and algorithmic analysis, allowing precise shape detection without requiring complete system redesign.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A digital camera system serves as an intermediary between the traditional pupillometer and the advanced shape analysis requirements. The camera captures high-resolution images that are then processed through specialized algorithms to extract precise pupillary shape information, bridging the gap between simple measurement and complex analysis.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Measurement precision

If automated shape detection algorithms are implemented, then accurate pupillary shape measurement is achieved, but processing time and computational requirements increase

Engineering Contradiction:
Improvepupillary shape measurement accuracyVSAvoidprocessing time
Core Design Contradiction:
Measurement precisionVSLoss of time

Solution Approach 1:

The system performs preliminary actions by capturing high-quality images with proper illumination and positioning before the actual shape analysis begins. The digital camera system pre-processes the image data through noise reduction and enhancement algorithms, so that the subsequent shape detection and grading algorithms work with optimized data, reducing their processing time.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The algorithm implements partial action by focusing computational resources on the most critical shape features and irregularity indicators. Rather than analyzing every pixel equally, the system identifies and concentrates processing power on key pupillary boundary regions and characteristic shape features, achieving accurate measurement with reduced overall processing time.

Inventive Principle:
Principle #16Partial or excessive action

3Adaptability or versatility

If multiple imaging modalities are integrated, then comprehensive neurological assessment capability is achieved, but device complexity and cost increase

Engineering Contradiction:
Improveneurological assessment capabilityVSAvoidimaging system complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The digital camera system is designed with multi-functionality to perform multiple imaging modalities including standard photography, spectral imaging, and speckle imaging. A single device platform supports diverse neurological assessments such as pupillary shape analysis, iris vasculature examination, and cyclotorsion measurement, eliminating the need for separate specialized devices for each function.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS20250311962A1Methods and devices for detecting, measuring and grading pupillary shapes and irregularities
Publication Date: 2025.10.09 NEUROPTICS INC
  • US20250311962A1 patent drawing
  • US20250311962A1 patent drawing

AI summary

A method for assessing pupillary shape using a pupillometer is described. The method includes capturing sequential images of a subject's pupil; analyzing the images using an image processing algorithm associated with the pupilometer to determine pupil shape characteristics, including ellipticity, eccentricity, and cyclotorsion; using an image processing mode associated with the pupilometer selected from speckle imaging and spectral imaging to enhance visualization of vascular structures with an iris of the pupil; comparing detected pupil shape characteristics against predetermined criteria to assess the presence of abnormalities; and outputting a binary status, graphical representation, or quantified measurement of the pupil shape on a display.