Digital Therapeutics Combination Therapy for Immune and Neural Function
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Solution Overview
Problem
Current treatments for neurodegenerative diseases like Alzheimer's disease are ineffective in preventing or slowing down disease progression, and there is a need for innovative therapies that can enhance neuroplasticity and immune function to improve patient outcomes.
Innovation Solution
A combination therapy approach using digital interventions such as sensory inhibition, substitution, and integration, alongside non-digital medical interventions, tailored to individual needs, to enhance neuro-connectivity and immune function, utilizing personalized digital platforms and medicinal agents.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If current treatments for neurodegenerative diseases are used, then disease progression is not effectively prevented or slowed, but combining digital interventions with medicinal agents increases treatment complexity
Solution Approach 1:
The patent combines digital interventions (sensory stimulation, cognitive training) with traditional medicinal agents into an integrated treatment protocol. This merging of therapeutic modalities addresses the limitation of single-modality treatments by creating a synergistic effect that enhances neuroplasticity and immune function while treating neurodegenerative diseases more effectively
Solution Approach 2:
The treatment protocol is segmented into distinct components: digital intervention modules (sensory stimulation, cognitive exercises), medicinal agent administration, and monitoring phases. This segmentation allows for systematic implementation and adjustment of each component while maintaining overall treatment coherence, managing the complexity through structured organization
2Reliability
If digital interventions are used to enhance neuroplasticity and immune function, then treatment efficacy is improved, but the device and system complexity increases
Solution Approach 1:
The digital platform is designed to perform multiple functions: delivering sensory stimulation, providing cognitive training, monitoring patient responses, and coordinating with medicinal agent administration. This multi-functionality consolidates what would otherwise require separate systems into a single integrated platform, improving efficacy while managing complexity through functional integration
Solution Approach 2:
The digital intervention system incorporates adaptive algorithms that automatically adjust stimulation parameters and exercise difficulty based on patient performance and physiological feedback. This self-adjusting capability reduces the need for constant manual calibration and complex external control systems, maintaining high efficacy while simplifying operational complexity
Data Source
AI summary
The presently disclosed subject matter relates to the field of digital therapeutics to improve immune function. A primary mode of delivering the digital therapeutics is using sensory means comprising: sensory inhibition, sensory substitution, sensory integration, or a combination thereof. The invention also provides combination therapies that comprise digital interventions together with non-digital interventions such as medicinal agents.


