Diode Laser Rhinitis Treatment Nerve Ablation

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Solution Overview

Problem

Current treatments for rhinitis, including surgical methods like vidian neurectomy and cryotherapy, face challenges such as complexity, complications like eye dryness, and the need for precise nerve identification, while medical therapies suffer from tachyphylaxis and daily medication reliance, lacking effective and sustainable solutions for both allergic and non-allergic rhinitis.

Innovation Solution

The use of a diode laser delivery device with an elongated fiber optic tip for laser ablation of the posterior nasal nerve, capable of reaching both superior and inferior branches, operating at 940 nanometers or 380-450 nanometers for targeted tissue heating to 60-70°C, minimizing collateral damage and allowing for office-based procedures with adjustable and disposable components.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If vidian neurectomy is performed to treat rhinitis, then treatment effectiveness is improved, but device complexity and surgical complexity increase significantly

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidsurgical complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent replaces complex mechanical dissection and identification procedures with laser energy delivery. The laser fiber directly ablates the posterior nasal nerve through the middle turbinate without requiring mechanical dissection of the sphenopalatine artery or identification of the nerve, thus substituting a complex mechanical surgical system with a simpler energy-based system that achieves the same therapeutic effect.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent extracts and removes the posterior nasal nerve through laser ablation without requiring extraction or manipulation of surrounding complex structures like the sphenopalatine artery. By targeting only the nerve tissue through the middle turbinate, the procedure eliminates the need to handle complex vascular and neural structures, reducing surgical complexity while maintaining treatment effectiveness.

Inventive Principle:
Principle #2Taking out (Extraction)

2Reliability

If vidian neurectomy is performed to treat rhinitis, then treatment effectiveness is improved, but harmful factors increase due to complications like severe bleeding and eye dryness

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidcomplications including bleeding and eye dryness
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent applies local quality by delivering laser energy precisely to the posterior nasal nerve location without affecting surrounding structures. The laser fiber is positioned through the middle turbinate to target only the nerve tissue, creating localized ablation that spares the sphenopalatine artery (preventing bleeding) and the ophthalmic nerve (preventing eye dryness), thus achieving effective treatment while minimizing harmful side effects.

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent converts the potential harm of laser energy into a beneficial selective ablation process. By controlling laser parameters and delivery location, the procedure uses thermal energy to precisely destroy only the posterior nasal nerve while the surrounding healthy tissues are protected, transforming what could be indiscriminate tissue damage into a selective therapeutic effect that eliminates the target nerve without causing complications.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

3Reliability

If cryotherapy is used to treat PNN region, then treatment effectiveness is improved, but manufacturing precision and targeting accuracy worsen due to inability to precisely identify the nerve

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidtargeting accuracy
Core Design Contradiction:
ReliabilityVSManufacturing precision

Solution Approach 1:

The patent replaces the mechanical cryotherapy probe with a laser fiber delivery system. The laser fiber can be precisely positioned and oriented through the middle turbinate under endoscopic visualization, allowing accurate targeting of the posterior nasal nerve. This substitution enables better control over the treatment zone and improved precision compared to the bulkier cryotherapy device that relies on freezing diffusion.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the physical parameter of the treatment modality from cryogenic temperatures to laser thermal energy. This parameter change allows for more precise control of the treatment zone, as laser energy can be delivered in a focused beam that can be precisely positioned and controlled in duration and intensity, whereas cryotherapy relies on thermal diffusion that is harder to confine to a precise target area.

Inventive Principle:
Principle #35Parameter changes

4Measurement precision

If meticulous dissection of SPA is performed to identify PNN, then targeting accuracy is improved, but device complexity and surgical time increase

Engineering Contradiction:
Improvenerve identification accuracyVSAvoiddissection complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts the posterior nasal nerve treatment effect without requiring extraction or dissection of the sphenopalatine artery. By accessing the nerve through the middle turbinate and using laser ablation, the procedure eliminates the need to perform meticulous dissection of the SPA, thus achieving nerve targeting while removing the complex dissection step entirely.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent replaces the mechanical dissection process with laser energy delivery. Instead of using surgical instruments to dissect and identify the nerve through the sphenopalatine artery region, the laser fiber is positioned through the middle turbinate and directly ablates the nerve, substituting a complex mechanical identification and dissection system with a simpler energy-based ablation system.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method provides a safe, minimally invasive, and effective treatment for rhinitis, reducing nasal congestion and rhinorrhea symptoms with significant symptom score improvements and reduced medication use, while being well-tolerated with rapid healing and minimal complications.

Implementation Method 1

The diode laser operates at approximately 940 nanometers. With the process, the heating of tissue by the device is done to approximately 60 to 70 degrees Celsius.

Methodology Applied
Scientific EffectLaser heating: Laser

Implementation Method 2

Skin and tissue temperature is raised to approximately 60-70°C during the treatment process.

Methodology Applied
Scientific EffectThermal ablation: Ablation

Implementation Method 3

a blue or green visible light laser with an optimal illumination treatment wavelength of 380-450 nanometers is also used with the present invention

Methodology Applied
Scientific EffectPhotothermal heating: Absorption (EM radiation)

Data Source

PatentEP4292555A1Laser treatment for rhinology
Publication Date: 2023.12.20 VALENT MADICAL INC
  • EP4292555A1 patent drawingFigure 1
  • EP4292555A1 patent drawingFigure 2
  • EP4292555A1 patent drawingFigure 3~4

AI summary

There is provided a process for treatment of rhinitis by diode laser ablation of the branches of the posterior nasal nerve. The diode laser delivery device with elongated fiber optic with its fiber tip is inserted through a patient's nostril and has the length, flexibility and a curvature to reach both above and under the patient's middle turbinate for treatment of both branches of the posterior nasal nerves. Skin and tissue temperature is raised to approximately 60-70□ with the process. A control knob on the laser delivery device moves from a first to a second position to move a camera attached to the laser delivery device. The fiber optic includes a distal fiber tip extending from a malleable sheath connected to the body for delivering light energy to a treatment area.