1,2-Dioxetane Derivative with Benzene Ring for High Luminous Efficiency
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Solution Overview
Problem
Existing 1,2-dioxetane derivatives for chemiluminescence applications do not achieve high luminous efficiency.
Innovation Solution
A compound with a benzene ring bound to the 3-position of 1,2-dioxetane, featuring a specific substituent such as —C≡C-E, where E represents various functional groups, or an aryl group with an electron withdrawing group, is used to enhance luminous efficiency.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Use of energy by moving object
If existing 1,2-dioxetane derivatives are used for chemiluminescence applications, then chemiluminescence function is achieved, but luminous efficiency is insufficient
Solution Approach 1:
The patent applies parameter changes by systematically modifying the chemical structure of 1,2-dioxetane derivatives. Specifically, it introduces specific substituent groups (such as —C≡C-E where E represents various functional groups, or aryl groups with electron withdrawing groups) at defined positions (ortho or para positions) of the benzene ring bound to the 3-position of 1,2-dioxetane. These structural parameter changes optimize the chemiluminescence reaction to achieve high luminous efficiency while minimizing energy loss.
2Use of energy by moving object
If high luminous efficiency is achieved through specific compound structure, then chemiluminescence performance is improved, but compound synthesis complexity increases
Solution Approach 1:
The patent applies local quality by introducing specific functional groups at particular positions of the molecular structure. Instead of uniformly complexifying the entire molecule, it places specific substituents (—C≡C-E groups or aryl groups with electron withdrawing groups) at the ortho or para positions of the benzene ring, which is bound to the 3-position of 1,2-dioxetane. This localized modification achieves high luminous efficiency while keeping the overall molecular structure relatively simple and synthetically accessible.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The described compound exhibits high luminous efficiency, enabling effective chemiluminescence methods, reagents, and assays for analyte detection.
Implementation Method 1
1,2-Dioxetane derivative is a compound capable of inducing chemiluminescence, triggered by a reaction with a chemical substance such as enzyme
Data Source
AI summary
Disclosed is a compound represented by formula [I] according to the specification, or a salt thereof, a composition comprising the compound, a chemiluminescence method using the compound, a method for measuring chemiluminescence signal, a reagent comprising the compound, a reagent kit comprising the compound and a method for assaying analyte.


