Dipeptide Ester Sweetener for E-Cigarette Vaporization
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Solution Overview
Problem
Existing electronic cigarette e-liquids face challenges with sweeteners like glucose and sucralose, which undergo thermal degradation, generating toxic compounds and posing health risks due to the formation of carcinogenic substances during vaporization, necessitating a sweetener that is vaporizable, high in sweetening power, and free from aftertaste and toxic by-products.
Innovation Solution
The use of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester as a sweetener in e-liquids, which maintains its sweetening power upon vaporization and does not produce toxic compounds, offering a safer alternative for electronic cigarettes.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Quantity of substance
If glucose or fructose are used as sweeteners in e-liquids, then high sweetening power is achieved, but thermal degradation generates toxic compounds including carcinogenic substances
Solution Approach 1:
The patent changes the chemical structure parameter of the sweetener from glucose/fructose to a dipeptide ester (N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester). This structural parameter change fundamentally alters the thermal degradation pathway, eliminating the formation of toxic compounds like furans and HMF while preserving high sweetening power.
2Quantity of substance
If sucralose is used as a sweetener in e-liquids, then high sweetening power is achieved, but thermal degradation produces irritating compounds and organochlorine substances
Solution Approach 1:
The patent changes the chemical composition parameter by replacing chlorine-containing sucralose with a chlorine-free dipeptide ester structure. This parameter change eliminates the generation of organochlorine compounds and irritating degradation products during vaporization, while maintaining high sweetening power through the preserved molecular structure.
3Quantity of substance
If a sweetener is used in e-liquids, then sweet flavor is provided, but the sweetener must remain stable during vaporization without producing toxic by-products
Solution Approach 1:
The patent employs a composite molecular structure combining L-α-aspartyl and L-phenylalanine 1-methyl ester units with a 3,3-dimethylbutyl substituent. This composite structure provides both the necessary stability during vaporization and high sweetening power, resolving the contradiction between flavor provision and thermal stability.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This solution provides a sweet flavor with high sweetening power that is stable during vaporization, avoiding the formation of toxic by-products and ensuring consumer safety, making it an ideal candidate for electronic cigarette compositions.
Implementation Method 1
This electronic cigarette works by vaporizing a liquid using electrical resistance
Implementation Method 2
vaporizing a liquid using electrical resistance
Data Source
AI summary
The invention relates to a composition intended for use as an electronic cigarette e-liquid or for addition to an electronic cigarette e-liquid, characterized in that it comprises N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester, a storage device comprising such a composition, an electronic cigarette comprising such a device, and the use of N-[N-(3,3-dimethylbutyl)-L-α-aspartyl]-L-phenylalanine 1-methyl ester as a sweetener or as a flavor enhancer in an electronic cigarette e-liquid composition.