Direct Cardiac Compression Device for Minimally Invasive Implantation
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Solution Overview
Problem
Current cardiac devices fail to effectively address aberrant mechanical environments in the heart, leading to progressive heart failure by not adequately modulating cardiac strain patterns, which contributes to further disease progression and limits the effectiveness of treatment strategies.
Innovation Solution
A Direct Cardiac Compression Device (DCCD) is introduced, which provides adjustable cardiac support and synchronous active assist through a minimally invasive surgical procedure, using a framework of retractable wire loops to position a compression device around the heart, allowing for direct cardiac compression without inverting the heart's curvature, thus modulating cardiac size and motion.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Power
If a cardiac device is implanted to provide cardiac support, then cardiac output and stroke work are improved, but the device complexity and surgical procedure difficulty increase
Solution Approach 1:
The compression device is nested within a delivery catheter system, allowing the device to be collapsed into a compact form for minimally invasive delivery through vascular access, then expanded at the target site to provide cardiac compression support
Solution Approach 2:
The device is segmented into multiple compression elements or chambers that can be independently controlled, allowing selective compression of different cardiac regions to optimize cardiac output while managing device complexity through modular design
2Reliability
If a cardiac device is implanted to modulate strain patterns, then restorative remodeling is promoted, but the surgical procedure invasiveness increases
Solution Approach 1:
The device replaces open surgical mechanical manipulation with a minimally invasive percutaneous delivery system, using catheter-based delivery to implant the compression device without requiring sternotomy or thoracotomy, thereby reducing surgical invasiveness while maintaining therapeutic efficacy
Solution Approach 2:
A delivery catheter system serves as an intermediary tool to implant the compression device through vascular access, mediating between the operator and the cardiac target site to eliminate the need for direct surgical exposure of the heart
3Power
If a compression device is used to increase cardiac output, then stroke work is improved, but end-diastolic pressure volume relationship may worsen
Solution Approach 1:
The compression device employs dynamic, adjustable compression forces that can be modulated in real-time based on cardiac cycle phase and patient response, allowing optimization of stroke work enhancement while preventing excessive end-diastolic pressure elevation through active control mechanisms
Solution Approach 2:
The device allows adjustment of compression pressure, duration, and timing parameters to optimize cardiac performance, enabling titration of therapeutic effect to improve stroke work while maintaining end-diastolic pressure within acceptable ranges through parameter optimization
Data Source
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AI summary
The present invention provides methods, systems, kits, and devices that aid in the positioning of a direct cardiac compression device about the heart.