Discovery Routing Engine for Anomaly Validation

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Solution Overview

Problem

Current automated systems for analyzing large volumes of medical and scientific data struggle to efficiently validate anomalies and connect experts with significant findings, often overwhelmed by false positives and limited to specific conditions or diseases, lacking a discovery component for new traits and patterns.

Innovation Solution

A cross-validation engine identifies and validates anomalies through descriptor-value pairs, filtering out insignificant deviations and matching confirmed anomalies with subject matter experts capable of taking action, utilizing a knowledge database and analytical engine to perform multivariate analysis and route relevant data for further analysis.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If automated systems analyze large volumes of data to identify anomalies, then the quantity of detected anomalies increases, but the number of false positives increases making expert review overwhelming

Engineering Contradiction:
Improveanomaly detection throughputVSAvoidanomaly validation accuracy
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The system segments the anomaly review process into multiple stages: initial automated detection, cross-validation filtering, and expert review of only validated anomalies. This segmentation reduces the volume of data requiring expert attention while maintaining high detection throughput.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A cross-validation engine is introduced as an intermediary between automated anomaly detection and expert review. This intermediary validates anomalies using multiple data sources and algorithms before presenting them to experts, filtering out false positives while preserving true anomalies.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Reliability

If automated systems focus on specific diseases or conditions, then analysis robustness improves, but diagnostic scope is limited

Engineering Contradiction:
Improvediagnostic robustnessVSAvoiddiagnostic scope
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The system implements a universal anomaly detection framework that can be applied across multiple diseases, conditions, and data types. The cross-validation engine and routing architecture are disease-agnostic, allowing the same system to handle diverse diagnostic scenarios while maintaining robustness through standardized validation processes.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The system allows dynamic adjustment of analysis parameters, thresholds, and validation criteria based on the specific disease or condition being investigated. This enables the system to optimize its behavior for different diagnostic contexts while maintaining a unified architecture, thus achieving both robustness and versatility.

Inventive Principle:
Principle #35Parameter changes

3Reliability

If human experts review all detected anomalies, then validation accuracy improves, but time consumption and resource requirements increase

Engineering Contradiction:
Improveanomaly validation accuracyVSAvoidexpert review time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The cross-validation engine performs preliminary validation of anomalies before they reach expert reviewers. By pre-filtering and pre-validating anomalies using automated cross-checks against multiple data sources, the system reduces the time experts need to spend on each anomaly while maintaining high validation accuracy.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system enables self-service validation where anomalies are automatically cross-checked against existing data, patterns, and criteria before human review. This self-validation process handles routine verification tasks, allowing experts to focus only on anomalies that require human judgment, thus reducing overall review time while maintaining accuracy.

Inventive Principle:
Principle #25Self-service

4Adaptability or versatility

If multiple data sources are integrated for analysis, then discovery capability improves, but system complexity increases

Engineering Contradiction:
Improvediscovery capabilityVSAvoidsystem architecture complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The routing engine acts as an intermediary that manages the integration of multiple data sources. It standardizes data ingestion, validation, and distribution across the system, reducing the complexity of integrating diverse sources while enabling comprehensive multi-source analysis for enhanced discovery capability.

Inventive Principle:
Principle #24Intermediary (Mediator)

Data Source

PatentUS20240355427A1Discovery routing systems and engines
Publication Date: 2024.10.24 NANT HOLDINGS IP LLC
  • US20240355427A1 patent drawing
  • US20240355427A1 patent drawing
  • US20240355427A1 patent drawing

AI summary

The inventive subject matter provides apparatus, systems, and methods that improve on the pace of discovering new practical information based on large amounts of datasets collected. In most cases, anomalies from the datasets are automatically identified, flagged, and validated by a cross-validation engine. Only validated anomalies are then associated with a subject matter expert who is qualified to take action on the anomaly. In other words, the inventive subject matter bridges the gap between the overwhelming amount of scientific data which can now be harvested and the comparatively limited amount analytical resources available to extract practical information from the data. Practical information can be in the form of trends, patterns, maps, hypotheses, or predictions, for example, and such practical information has implications in medicine, in environmental sciences, entertainment, travel, shopping, social interactions, or other areas.