Disinfection Composition Stability via Phytic Acid and Citric Acid

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Solution Overview

Problem

Botanical disinfection compositions face challenges with poor chemical stability and reduced disinfection effect due to the addition of auxiliary materials, which can weaken the sterilization effect and shorten the product's validity period.

Innovation Solution

A disinfection composition comprising disinfection essential oils, polyethylene glycol hydrogenated castor oil, phytic acid, citric acid, C2-C3 monohydric alcohol, and water in specific ratios, along with azelaic acid and cosolvents, to enhance chemical stability and disinfection efficacy, while minimizing the use of auxiliary materials.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Stability of the object's composition

If auxiliary materials (Tween 80, ethanol, propylene glycol, disodium EDTA) are added to form an emulsion to improve physical stability, then physical stability is improved, but chemical stability deteriorates and active ingredient content decreases during storage

Engineering Contradiction:
Improvephysical stabilityVSAvoidchemical stability
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent changes the chemical composition parameters by replacing traditional emulsion-forming auxiliary materials (Tween 80, disodium EDTA) with a novel combination of polyethylene glycol hydrogenated castor oil as the sole emulsifier, phytic acid, and citric acid. This parameter change resolves the contradiction by achieving both physical stability (through effective emulsification) and chemical stability (by eliminating ingredients that cause active ingredient degradation).

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent extracts and removes harmful auxiliary materials from the formulation. Specifically, it eliminates Tween 80 and disodium EDTA which were causing chemical instability and active ingredient loss, retaining only the essential emulsifying components needed for physical stability while improving overall chemical stability.

Inventive Principle:
Principle #2Taking out (Extraction)

2Stability of the object's composition

If auxiliary materials are added to improve stability, then stability is improved, but disinfection effect decreases

Engineering Contradiction:
ImprovestabilityVSAvoiddisinfection effect
Core Design Contradiction:
Stability of the object's compositionVSReliability

Solution Approach 1:

The patent optimizes the concentration parameters of auxiliary materials, reducing them to minimal effective amounts. Polyethylene glycol hydrogenated castor oil is used at 3-8 parts, phytic acid at 0.05-0.5 parts, and citric acid at 0.05-0.5 parts per 2.2-4.8 parts of essential oil. This minimalistic approach maintains stability while preserving the dominant disinfection effect of the essential oils.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent applies partial action by using the smallest necessary amounts of auxiliary materials to achieve stability. Rather than using large quantities of emulsifiers and stabilizers, it employs minimal concentrations that are sufficient for stability but do not interfere with the disinfection efficacy of the essential oil active ingredients.

Inventive Principle:
Principle #16Partial or excessive action

3Stability of the object's composition

If emulsion is used to improve physical stability, then physical stability is improved, but product validity period shortens due to reduced active ingredient content

Engineering Contradiction:
Improvephysical stabilityVSAvoidproduct validity period
Core Design Contradiction:
Stability of the object's compositionVSDuration of action of stationary object

Solution Approach 1:

The patent removes ingredients that cause active ingredient degradation during storage. By eliminating Tween 80 and disodium EDTA from the formulation, it prevents the chemical reactions that lead to active ingredient loss, thereby extending the product's validity period while maintaining physical stability through the alternative emulsifier system.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent uses phytic acid and citric acid as natural, stable, and inexpensive stabilizing agents that provide long-term protection without degrading the active ingredients. These materials offer sustained stability throughout the product's shelf life, effectively extending the validity period.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition achieves improved chemical stability and enhanced disinfection effect, maintaining effectiveness after storage, with a synergistic action of citric acid and ethanol, and phytic acid replacing EDTA for better stability, resulting in a longer storage period and faster disinfection action.

Implementation Method 1

Tween 80, ethanol, propylene glycol and disodium EDTA were introduced to form an emulsion

Methodology Applied
Scientific EffectEmulsion: Emulsion

Implementation Method 2

polyethylene glycol hydrogenated castor oil

Methodology Applied
Scientific EffectSurfactant: Surfactant

Implementation Method 3

0.05-0.5 parts of phytic acid, 0.05-0.5 parts of citric acid

Methodology Applied
Scientific EffectChelation:

Data Source

PatentUS11517021B2Disinfection composition and preparation method therefor and use thereof
Publication Date: 2022.12.06 NANJING HEJIYUAN BIOLOGICAL TECH CO LTD

AI summary

Provided is a disinfection composition, preparation method therefor and use thereof. The disinfection composition comprises the following raw materials in parts by weight: 2.2-4.8 parts of disinfection essential oil, 3-8 parts of polyethylene glycol hydrogenated castor oil, 0.05-0.5 parts of phytic acid, 0.05-0.5 parts of citric acid, 20-40 parts of a C2-C3 monohydric alcohol, and 45-62.1 parts of water. The disinfection composition of the present invention has significantly improved chemical stability, and still has good disinfection effect after storage for 3 months at 37° C., and has a significantly improved disinfection effect, a shortened action time, and an increased killing log value.