Disposable Cap Supply for Preanalytical Systems

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Solution Overview

Problem

Existing methods for capping and decapping vessels containing biological samples in analytical systems require significant hardware and complexity, leading to inefficiencies and increased costs, as well as the need for additional space and complex interactions within the system.

Innovation Solution

A method and system utilizing a disposable cap supply with caps in a predefined geometrical arrangement, where a laterally and vertically moveable robotic manipulator retrieves and applies caps to vessels within a preanalytical system, eliminating the need for dedicated hardware and minimizing system complexity by using existing robotic components for cap handling and transportation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a removable cartridge is used to recap vessels within an analyzer, then the capping function is achieved, but a considerable extent of hardware inside the analyzer is required

Engineering Contradiction:
Improvecapping functionVSAvoidhardware extent
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The patent employs a disposable cap supply cartridge that is externally loaded and then discarded after use, eliminating the need for complex internal hardware mechanisms for cap storage and retrieval. The cartridge is a simple, low-cost component that can be replaced rather than maintained, significantly reducing the hardware complexity inside the analyzer while maintaining the capping function.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If dedicated hardware is used for cap handling, then capping reliability is improved, but system complexity and space requirements increase

Engineering Contradiction:
Improvecapping reliabilityVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent extracts the cap supply and cap storage function from the main analyzer body and places it in an external disposable cartridge. This separation allows the analyzer to use its existing robotic manipulator for cap retrieval, eliminating the need for dedicated internal cap handling hardware while maintaining reliable capping through the precision of the existing robotic system.

Inventive Principle:
Principle #2Taking out (Extraction)

3Object-affected harmful factors

If a composite plate with stored caps is used, then contamination is avoided, but additional hardware and space are required within the system

Engineering Contradiction:
Improvecontamination avoidanceVSAvoidsystem space
Core Design Contradiction:
Object-affected harmful factorsVSVolume of stationary object

Solution Approach 1:

The patent uses a disposable cap supply cartridge that is sealed and externally stored, preventing contamination until the caps are needed. The cartridge is discarded after use, eliminating the need for permanent, space-consuming contamination prevention mechanisms within the analyzer. The external storage and disposal approach maintains contamination avoidance while minimizing system space requirements.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Data Source

PatentEP2801828B1Supplying method for disposable cap supply and preanalytical system comprising disposable cap supply
Publication Date: 2021.03.03 F HOFFMANN LA ROCHE & CO AG
  • EP2801828B1 patent drawingFigure 1
  • EP2801828B1 patent drawingFigure 2A~2B
  • EP2801828B1 patent drawingFigure 2C~2D

AI summary

The invention relates to a method for capping vessels containing biological samples. The method comprises providing a cap supply with a plurality of caps for the vessels within compartments in a predefined geometrical arrangement. The cap supply is introduced through an interface into a preanalytical system comprising a housing. For this purpose, it is reversibly docked to a feeder for inserting the cap supply into the preanalytical system and retrieving it therefrom. Subsequently, a cap is retrieved from the supply by a robotic manipulator, and transported to a workstation holding the vessels. A vessel is then capped using the manipulator. The steps from introducing the cap supply into the preanalytical system to capping a vessel are then repeated a certain number of times or until all caps of the supply have been retrieved. Finally, the cap supply is retrieved from the preanalytical system. The invention also provides a preanalytical system and a cap supply for capping vessels containing biological samples.