Cryoliner

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Current methods for cleaning and sanitizing dewars that store products at cryogenic temperatures are time-consuming and can cause damage due to thermal cycling, necessitating a solution that prevents cross-contamination without warming the dewar.

Innovation Solution

A protective liner is positioned within the dewar, featuring tabs for interlocking with the dewar's notch, a temperature sensor channel, and an accessory holder, which prevents cross-contamination and reduces cleaning time by allowing the dewar to be reused without warming.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the dewar is warmed and cleaned using a multi-step cleaning and sanitization process, then cross-contamination is prevented, but the cleaning time increases to approximately 4 days and thermal damage may occur

Engineering Contradiction:
Improvecross-contamination preventionVSAvoidcleaning time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The invention divides the cleaning system into two separate components: a reusable dewar and a disposable protective liner. The liner is segmented from the dewar, allowing the liner to be discarded after use while the dewar remains clean and ready for immediate reuse, eliminating the 4-day cleaning process.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The protective liner is designed as a disposable, low-cost component that is discarded after a single use. This eliminates the need for time-consuming cleaning and sanitization of the expensive dewar, reducing cleaning time from 4 days to minimal time for liner replacement.

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If the dewar is warmed for cleaning, then sanitization is achieved, but thermal cycling causes damage to the dewar or vacuum seal

Engineering Contradiction:
ImprovesanitizationVSAvoiddewar structural integrity
Core Design Contradiction:
ReliabilityVSStrength

Solution Approach 1:

The protective liner acts as an intermediary barrier between the product and the dewar. It absorbs the sanitization function through disposal, protecting the dewar from thermal stress and structural damage that would result from repeated warming and cooling cycles.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The cleaning and sanitization function is extracted from the dewar itself and transferred to the disposable liner. The liner is removed and discarded after use, taking with it any contamination, while the dewar remains intact and undamaged.

Inventive Principle:
Principle #2Taking out (Extraction)

3Reliability

If specific-use shipping containers are used, then cross-contamination is prevented, but asset utilization decreases due to dedicated containers for each product

Engineering Contradiction:
Improvecross-contamination preventionVSAvoidasset utilization
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

The system segments the containment function into a reusable dewar and a disposable liner. This allows one dewar to serve multiple products by simply replacing the liner, increasing asset utilization while maintaining cross-contamination prevention.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The dewar is designed to be universal and multi-functional, capable of storing different products by simply changing the disposable liner. This eliminates the need for dedicated dewars for each product, thereby increasing asset utilization and productivity.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Data Source

PatentUS12298052B2Cryoliner
Publication Date: 2025.05.13 CRYOPORT INC
  • US12298052B2 patent drawing
  • US12298052B2 patent drawing
  • US12298052B2 patent drawing

AI summary

Methods, systems, devices and/or apparatuses for a protective liner that protects products and/or commodities from cross-contamination during transport and/or storage using a cryogenic shipping container. The protective liner lines a shipping container, such as a dewar. The protective liner is positioned within the shipping container. The protective liner includes one or more tabs positioned on a perimeter of the protective liner. The one or more tabs are configured to interlock with a notch on an inside surface of the shipping container. The protective liner includes a clearance channel on a side of the protective barrier and configured to guide a temperature sensor lead wire.