Divided Counter Electrode Biosensor for Blood Volume Detection
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Solution Overview
Problem
Conventional biosensors often inaccurately measure blood glucose levels due to insufficient blood samples, leading to incorrect results, and the addition of detection electrodes increases manufacturing costs and complexity.
Innovation Solution
A biosensor design with a divided counter electrode and insulating mask within the capillary, allowing for reliable detection of blood presence and quantity without additional detection electrodes, using the shape and position of the counter electrode to differentiate between sufficient and insufficient blood samples based on response current patterns.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If a detection electrode is added to determine blood introduction, then measurement reliability is improved, but device complexity and manufacturing cost increase
Solution Approach 1:
The counter electrode is designed to serve dual functions: as a working electrode for glucose measurement and as a detection electrode for blood introduction detection. By positioning part of the counter electrode downstream in the blood flow direction, it can detect blood presence through current changes while simultaneously participating in the amperometric measurement process, eliminating the need for a separate detection electrode.
Solution Approach 2:
The invention merges the detection electrode function into the counter electrode structure. The counter electrode is divided into multiple parts, with the downstream portion serving both as a measurement electrode and a detection electrode, combining what were previously separate functional elements into a unified structure.
2Reliability
If a detection electrode is added to determine blood introduction, then measurement reliability is improved, but manufacturing cost increases
Solution Approach 1:
The counter electrode is designed to serve dual functions: as a working electrode for glucose measurement and as a detection electrode for blood introduction detection. By positioning part of the counter electrode downstream in the blood flow direction, it can detect blood presence through current changes while simultaneously participating in the amperometric measurement process, eliminating the need for a separate detection electrode.
Solution Approach 2:
The invention merges the detection electrode function into the counter electrode structure. The counter electrode is divided into multiple parts, with the downstream portion serving both as a measurement electrode and a detection electrode, combining what were previously separate functional elements into a unified structure.
3Speed
If blood introduction is detected by current threshold, then detection speed is improved, but measurement precision deteriorates due to insufficient blood amount
Solution Approach 1:
The downstream portion of the counter electrode detects blood introduction in advance before the blood reaches the working electrode. This preliminary detection allows the system to verify sufficient blood presence before initiating the glucose measurement, ensuring measurement precision while maintaining quick detection response.
Solution Approach 2:
The system uses the current detected by the downstream counter electrode portion as feedback to determine whether sufficient blood has been introduced. This feedback mechanism ensures that glucose measurement only proceeds when adequate blood is present, improving measurement precision while maintaining rapid detection through the threshold-based approach.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This design effectively detects insufficient blood samples, preventing incorrect measurements and maintaining a simple, cost-effective structure by utilizing existing electrodes to determine blood presence and quantity, enhancing measurement reliability and reducing manufacturing costs.
Implementation Method 1
measures the blood glucose level by an electrochemical method and includes a substrate 80 to which a cover 82 is bonded via a spacer 81. The spacer 81 is formed with a slit 83, which defines a capillary 84 between the substrate 80 and the cover 82. A reagent layer 85 is provided in the capillary 84, so that a reaction field for reaction between blood and a reagent contained in the reagent layer 85 is provided when blood is introduced into the capillary.
Implementation Method 2
The spacer 81 is formed with a slit 83, which defines a capillary 84 between the substrate 80 and the cover 82
Data Source
Figure 1~2
Figure 3
Figure 4A~4D
AI summary
The present invention relates to an analytical tool 1 which includes a flow path for moving a sample, and a working electrode 15 and a counter electrode 16 including active portions 15c, 16c, 16d for coming into contact with the sample supplied to the flow path and which is mounted in use to an analytical apparatus. The active portions 16c, 16d of the counter electrode 16 include a first active portion 16c and a second active portion 16d divided within the flow path. The working electrode 15 and the counter electrode 16 include contact ends 15a, 16a for coming into contact with terminals of an analytical apparatus when the analytical tool 1 is mounted to the analytical apparatus. At least one of the working electrode 15 and the counter electrode 16 includes a first electrode portion 16B which includes the contact end 16a and the first active portion 16c and a second electrode portion 16C which includes the second active portion 16d.