Double Half RF Pulses for UTE Eddy Current Reduction

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Solution Overview

Problem

Ultrashort echo time (UTE) imaging faces challenges in achieving accurate slice selectivity and R2* quantitation due to eddy currents, which distort the slice profile and introduce errors in T2 measurements, especially for short T2 species like musculoskeletal tissues, lung, and frozen tissue during cryoablation, as conventional techniques are limited by long echo times and sensitive to gradient imperfections.

Innovation Solution

The Double Half RF (DHRF) and Inverted Double Half RF (IDHRF) pulses are introduced, which split a conventional full-sinc RF pulse into two halves with a time interval, improving slice selectivity for long T2 components and suppressing unwanted long T2 signals, thereby reducing the impact of eddy currents and enhancing the accuracy of short T2 imaging and quantitation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional full-sinc RF pulses are used for UTE imaging, then the imaging can be performed with standard equipment, but eddy currents distort the slice profile and reduce measurement precision

Engineering Contradiction:
ImproveR2* quantitation accuracyVSAvoideddy current distortion
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The conventional full-sinc RF pulse is divided into two half-pulses separated by a time interval. This segmentation allows the first half-pulse to excite both short and long T2 species while the second half-pulse selectively refocuses only long T2 signals, thereby suppressing eddy current-induced artifacts and improving R2* quantitation accuracy for short T2 tissues.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The pulse sequence employs periodic application of half-pulses with a specific time interval between them. This periodic structure enables selective refocusing of long T2 signals while allowing short T2 signals to decay, creating a rhythm that suppresses eddy current effects and enhances measurement precision.

Inventive Principle:
Principle #19Periodic action

2Measurement precision

If conventional RF pulses are used, then the pulse sequence is simple, but slice selectivity is poor and long T2 signals contaminate short T2 imaging

Engineering Contradiction:
Improveslice selectivityVSAvoidpulse sequence complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The RF pulse is segmented into two distinct half-pulses with different functions: the first half-pulse provides broad excitation for both short and long T2 species, while the second half-pulse provides selective refocusing for long T2 signals. This segmentation achieves superior slice selectivity and signal suppression without requiring complex gradient characterization.

Inventive Principle:
Principle #1Segmentation

3Loss of time

If standard RF pulses are used for imaging, then the imaging speed is adequate, but the echo time is too long for accurate short T2 measurement

Engineering Contradiction:
Improveecho timeVSAvoidshort T2 measurement accuracy
Core Design Contradiction:
Loss of timeVSMeasurement precision

Solution Approach 1:

The pulse sequence rushes through the excitation and refocusing process by using half-pulses with a minimal time interval between them. This allows the acquisition to occur at ultra-short echo times, capturing short T2 signals before they decay, thereby reducing time loss and improving measurement accuracy.

Inventive Principle:
Principle #21Skipping (Rushing through)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

These pulses significantly improve slice selectivity and R2* quantitation accuracy, reducing the influence of eddy currents and providing better contrast and signal-to-noise ratio for short T2 species by effectively suppressing long T2 signals, thus offering an alternative to time-consuming gradient characterization methods.

Implementation Method 1

nuclear magnetic moments are excited at specific spin precession frequencies which are proportional to the local magnetic field

Methodology Applied
Scientific EffectNuclear spin precession: Precession

Implementation Method 2

each nuclear spin responds to four different effects: precession about the main magnetic field, nutation about an axis perpendicular to the main field, and both transverse and longitudinal relaxation

Methodology Applied
Scientific EffectTransverse relaxation:

Implementation Method 3

nutation about an axis perpendicular to the main field

Methodology Applied
Scientific EffectNutation:

Implementation Method 4

The radio-frequency signals resulting from the precession of these spins are received using pickup coils

Methodology Applied
Scientific EffectElectromagnetic induction: Electromagnetic Induction

Data Source

PatentUS7592806B2Double half RF pulses for reduced sensitivity to eddy currents in UTE imaging
Publication Date: 2009.09.22 THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIV
  • US7592806B2 patent drawing
  • US7592806B2 patent drawing
  • US7592806B2 patent drawing

AI summary

A method for creating a magnetic resonance image of an object with at least a first species and a second species, wherein the first species has a first T2 time and the second species has a second T2 time longer than the first T2 time is provided. An excitation with an ultra short echo time using a pulse is provided, comprising a first subpulse that creates a transverse magnetization component for the first species and the second species and a second subpulse that creates a transverse magnetization for the first species and substantially returns the second species to a longitudinal axis, wherein the transverse magnetization component substantially decays for the first species during an interval between the first subpulse and the second subpulse. At least one echo is read. A magnetic resonance image is created from the at least one echo.