Double-Sided Grating Waveguide Biosensor for Mass Production

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Solution Overview

Problem

Conventional optical biosensors with single-sided grating structures are difficult to manufacture and require complex measurement instruments to detect light beam variations, limiting their accuracy and mass production potential.

Innovation Solution

A double-sided grating waveguide biosensor with a plastic grating and a high-refraction index waveguide layer, integrated with a channel chip and recognition molecule layer, allows for efficient light coupling and detection of sample properties through variations in light beam intensity, simplifying the detection process and enabling mass production.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If a single-sided grating structure is used, then the manufacturing process is simpler, but the light coupling efficiency and detection sensitivity are limited

Engineering Contradiction:
Improvemanufacturing simplicityVSAvoiddetection sensitivity
Core Design Contradiction:
Ease of manufactureVSMeasurement precision

Solution Approach 1:

The patent transitions from a single-sided grating structure to a double-sided grating structure, adding a second grating layer on the opposite side of the waveguide. This dimensional change enables light to be coupled from both directions, significantly improving light coupling efficiency and detection sensitivity while maintaining manufacturing simplicity through the use of imprinting technology

Inventive Principle:
Principle #17Another dimension (Dimensionality change)

2Manufacturing precision

If conventional grating manufacturing methods (imprinting, ion erosion, holographic technique) are used, then grating structures can be formed, but the processes are too complex for mass production

Engineering Contradiction:
Improvegrating structure formationVSAvoidmass production capability
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The patent employs imprinting technology using sacrificial master molds to create the grating structures. The master molds are used to imprint multiple copies of the grating pattern onto waveguide substrates, enabling high-volume production. This approach replaces complex ion erosion or holographic techniques with a simpler, more scalable imprinting process that can be mass-produced

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

Solution Approach 2:

The patent optimizes the grating parameters including period, depth, and width to achieve effective light coupling while maintaining compatibility with imprinting manufacturing. By carefully selecting grating parameters, the system achieves high detection sensitivity through a manufacturing process that is suitable for mass production

Inventive Principle:
Principle #35Parameter changes

3Measurement precision

If angle and wavelength variations are measured for detection, then the detecting purpose is achieved, but complex measurement instruments are required

Engineering Contradiction:
Improvedetection capabilityVSAvoidmeasurement instrument complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent replaces complex angular and wavelength measurement systems with a simplified intensity-based detection system. The double-sided grating structure is designed so that changes in the sample's properties directly modulate the intensity of coupled light, allowing detection using simple photodetectors rather than complex spectrometers or angular measurement devices

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Productivity

If a plastic grating with gaps is used, then mass production and cost reduction are achieved, but manufacturing precision challenges arise

Engineering Contradiction:
Improvemass production capabilityVSAvoidgrating structure precision
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The patent carefully controls critical grating parameters including period, depth, and gap dimensions to ensure effective light coupling despite the use of plastic materials and imprinting manufacturing. By optimizing these parameters, the system achieves both mass production capability and sufficient manufacturing precision for reliable detection

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The double-sided grating waveguide biosensor enhances detection sensitivity and range, maintains consistent sensitivity with varying coupling angles and positions, and simplifies the detection process by measuring light beam intensity, achieving high resolution and cost-effective mass production.

Implementation Method 1

The double-sided grating structure comprises two waveguide grating parts corresponding to each other... When the light beam is coupled into the waveguide layer via the double-sided grating structure and propagates along the waveguide layer

Methodology Applied
Scientific EffectDiffraction: Diffraction

Implementation Method 2

When the light beam is coupled into the waveguide layer via the double-sided grating structure and propagates along the waveguide layer

Methodology Applied
Scientific EffectTotal internal reflection: Total Internal Reflection

Implementation Method 3

the double-sided grating waveguide biosensor of the present invention detects the properties of the sample solution via the variations of a light beam intensity of the light beam penetrating out of the waveguide layer

Methodology Applied
Scientific EffectRefraction: Refraction

Data Source

PatentUS9140857B2Double-sided grating waveguide biosensor
Publication Date: 2015.09.22 NATIONAL CHUNG CHENG UNIV
  • US9140857B2 patent drawing
  • US9140857B2 patent drawing
  • US9140857B2 patent drawing

AI summary

Disclosed is a double-sided grating waveguide biosensor. The double-sided grating waveguide biosensor is used to sense the properties of a sample solution. The double-sided grating waveguide biosensor comprises a sequential stack of a plastic grating having a grating part, a waveguide layer having a double-sided grating structure, and a channel chip. Furthermore, the sample solution is guided into the channel chip; the light beam is coupled into the waveguide layer via the double-sided grating structure, propagates in the waveguide layer, and penetrates outward. The double-sided waveguide biosensor detects the properties of the sample solution via a variation of a light beam intensity of the outgoing light beam.