Double Syringe Bone Marrow Aspiration Device

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Solution Overview

Problem

Conventional bone marrow aspiration methods cause patient discomfort and anxiety due to negative pressure, which slows the aspiration process and risks damaging the bone marrow sample.

Innovation Solution

A double syringe assembly with a needle assembly that aspirates bone marrow through an outer tube while simultaneously injecting fluid, such as saline or anesthetic, through an inner tube to maintain equal fluid and marrow volumes, reducing negative pressure and improving the ease of marrow withdrawal.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If conventional aspiration methods are used to extract bone marrow, then the procedure can be performed, but patient discomfort and anxiety increase due to negative pressure

Engineering Contradiction:
Improvepatient discomfort and anxietyVSAvoidaspiration device structure
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

The device divides the single aspiration function into two separate syringes: a distal syringe for aspiration and a proximal syringe for fluid injection. This segmentation allows independent control of fluid injection and marrow extraction, enabling positive pressure maintenance while reducing patient discomfort during the procedure.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The inner tube is nested within the outer tube, with the inner tube serving as a guide for needle insertion and the outer tube performing the actual aspiration. This nested structure allows simultaneous fluid injection through the inner tube while aspirating marrow through the outer tube, resolving the contradiction between device complexity and patient comfort.

Inventive Principle:
Principle #7Nested doll (Nesting)

2Productivity

If negative pressure is applied during aspiration, then bone marrow can be extracted, but the aspiration rate slows down

Engineering Contradiction:
Improveaspiration rateVSAvoidnegative pressure in bone
Core Design Contradiction:
ProductivityVSStress or pressure

Solution Approach 1:

Fluid is injected into the bone marrow space through the proximal syringe before and during the aspiration process. This preliminary action of fluid injection prevents negative pressure buildup, maintaining positive pressure conditions that enable faster aspiration rates without causing patient discomfort or slowing the procedure.

Inventive Principle:
Principle #10Preliminary action

3Productivity

If excessive aspiration force is applied, then bone marrow can be withdrawn faster, but damage to the bone marrow sample occurs via hemolysis

Engineering Contradiction:
Improvemarrow withdrawal speedVSAvoidbone marrow sample integrity
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The fluid injected through the proximal syringe acts as an intermediary medium that maintains positive pressure in the bone marrow space. This intermediary fluid allows for controlled, gentle aspiration through the distal syringe, enabling faster withdrawal rates while preventing excessive force that would cause hemolysis or sample damage.

Inventive Principle:
Principle #24Intermediary (Mediator)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Significantly reduces patient pain and anxiety, increases the rate of bone marrow withdrawal, and minimizes the risk of damaging the bone marrow sample by maintaining positive pressure during the aspiration process.

Implementation Method 1

the proximal syringe injects fluid into the target area through the inner tube of the needle at the same rate in which the bone marrow is extracted, the plunger controlling the flow volume of each syringe chamber such that the fluid volume ejected by the chamber of the proximal syringe is equal to the bone marrow volume received by the chamber of the distal syringe

Methodology Applied
Scientific EffectFluid displacement:

Implementation Method 2

maintaining positive pressure during the aspiration process

Methodology Applied
Scientific EffectPressure balance:

Data Source

PatentUS10973500B2Device and method for aspirating bone marrow
Publication Date: 2021.04.13 FOREVER LABS INC
  • US10973500B2 patent drawing
  • US10973500B2 patent drawing
  • US10973500B2 patent drawing

AI summary

A device and method for aspirating bone barrow. The device includes a double syringe assembly having a distal syringe and a proximal syringe coupled to the distal syringe. A plunger includes a distal end disposed within a barrel of the distal syringe and a proximal end disposed within a barrel of the proximal syringe. A needle assembly is coupled to the double syringe assembly and includes a needle having an outer tube and an inner tube disposed within the outer tube. Upon actuation of the plunger, the distal syringe aspirates bone marrow through the outer tube of the needle and into a chamber of the distal syringe. At the same time, the proximal syringe injects fluid through the inner tube of the needle at the same rate in which the bone marrow is aspirated.