Drug Delivery Cartridge Assembly With Coding and Permanent Fixing

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Solution Overview

Problem

Existing drug delivery devices face risks of incorrect cartridge insertion, damage to glass cartridges, and difficulty in accommodating cartridges of varying dimensions due to a lack of secure and dedicated connection mechanisms.

Innovation Solution

A cartridge assembly with a fixing member that permanently secures the cartridge to a holder, preventing axial and rotational movement, and includes coding features to ensure compatibility with the correct drive mechanism, allowing standard cartridges to be used with different dimensions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a releasable connection between cartridge holder and housing is used, then cartridge replacement is enabled, but risk of incorrect cartridge insertion increases

Engineering Contradiction:
Improvecartridge replacementVSAvoidcorrect cartridge insertion
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The cartridge holder includes asymmetric coding features (such as specific geometric shapes, protrusions, or orientational markings) that correspond to matching features in the drive mechanism housing. This asymmetric coding system ensures that only the correct cartridge holder can be connected to the correct housing, preventing incorrect cartridge insertion while maintaining ease of replacement through a simple snap-fit or latching mechanism.

Inventive Principle:
Principle #4Asymmetry

2Ease of manufacture

If standard glass cartridges are used, then manufacturing simplicity is maintained, but cartridge damage risk increases

Engineering Contradiction:
Improvecartridge manufacturingVSAvoidcartridge damage
Core Design Contradiction:
Ease of manufactureVSObject-affected harmful factors

Solution Approach 1:

The cartridge holder incorporates protective features such as recessed mounting areas, cushioning structures, or protective coatings that shield the glass cartridge from mechanical damage during insertion, handling, and operation. The holder design includes features like rounded edges, adequate clearance, and stress-distributing contact points that prevent cracks and breaks in the fragile glass cartridge while maintaining manufacturing simplicity.

Inventive Principle:
Principle #11Beforehand cushioning (Prior cushioning)

3Reliability

If a fixed cartridge holder design is used, then connection reliability is improved, but adaptability to different cartridge dimensions is reduced

Engineering Contradiction:
Improveconnection stabilityVSAvoidcartridge dimension compatibility
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The cartridge holder employs adjustable or flexible features such as spring-loaded clamps, movable retaining arms, or elastic deformation elements that can dynamically adapt to different cartridge dimensions. These dynamic features maintain reliable connection through elastic forces while accommodating variations in cartridge length, diameter, or overall size, enabling a single holder design to support multiple cartridge types.

Inventive Principle:
Principle #15Dynamics

4Reliability

If coding features are added to prevent wrong cartridge insertion, then patient safety is improved, but device complexity increases

Engineering Contradiction:
Improvepatient safetyVSAvoidcartridge holder structure
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The cartridge holder incorporates visual coding features such as color-coded rings, stripes, or markings on the holder and corresponding cartridges. These color changes or visual indicators provide immediate, intuitive feedback to users about compatibility, preventing incorrect insertion without requiring complex mechanical interlocks or additional electronic verification systems. The coding remains simple and easily manufacturable while significantly improving patient safety.

Inventive Principle:
Principle #32Color changes

Data Source

PatentUS12427259B2Cartridge assembly for a drug delivery device and method for assembling the same
Publication Date: 2025.09.30 SANOFI SA(FR)
  • US12427259B2 patent drawing
  • US12427259B2 patent drawing
  • US12427259B2 patent drawing

AI summary

A cartridge assembly for a drug delivery device can include: a cartridge holder, a cartridge containing a drug, and a fixing member, wherein the cartridge holder includes an interior cartridge holding section, the cartridge being arranged in the cartridge holding section, wherein the fixing member is axially secured to the cartridge holder and secures the cartridge permanently in the cartridge holder.