Packaged Drug Container Dual Oxygen Scavenger System

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing medicine-filled containers do not effectively remove oxygen quickly and continuously, which can lead to medicine degradation, as they rely on passive oxygen scavenging methods that are not sufficient for maintaining a low-oxygen environment over time.

Innovation Solution

A packaged medicine-filled container with a resin-made container and a sealed, hardly oxygen-permeable packaging body that incorporates both moisture-dependent and self-reacting type oxygen scavengers to rapidly remove oxygen initially and maintain a low-oxygen atmosphere through continuous scavenging.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a single type of oxygen scavenger is used in the packaging body, then the structure is simple, but oxygen cannot be removed quickly and continuously

Engineering Contradiction:
Improveoxygen removal effectivenessVSAvoidoxygen scavenger system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines two different types of oxygen scavengers (moisture-dependent type and self-reacting type) into a single packaging system. The moisture-dependent type oxygen scavenger quickly removes oxygen in the early period by reacting with moisture and oxygen, while the self-reacting type oxygen scavenger continuously removes oxygen over time. This merging of different scavenging mechanisms resolves the contradiction by achieving both quick initial oxygen removal and continuous long-term oxygen removal without requiring complex separate systems.

Inventive Principle:
Principle #5Merging (Combining)

Solution Approach 2:

The moisture-dependent type oxygen scavenger performs preliminary action by quickly removing oxygen in the early period of storage. This initial rapid oxygen removal creates a low-oxygen environment quickly, which is then maintained by the self-reacting type oxygen scavenger. This preliminary action principle allows the system to achieve fast oxygen removal initially while maintaining simplicity through the coordinated action of both scavenger types.

Inventive Principle:
Principle #10Preliminary action

2Speed

If passive oxygen scavenging is used, then the packaging structure is simple, but oxygen removal speed is insufficient for medicine stabilization

Engineering Contradiction:
Improveoxygen removal speedVSAvoidmedicine stabilization reliability
Core Design Contradiction:
SpeedVSReliability

Solution Approach 1:

The patent merges two oxygen scavenging mechanisms with different operational characteristics: the moisture-dependent type provides fast initial oxygen removal speed, while the self-reacting type ensures reliable continuous oxygen removal. This combination resolves the contradiction between speed and reliability by leveraging the strengths of both scavenger types - the moisture-dependent type achieves rapid oxygen removal to stabilize medicine quickly, while the self-reacting type maintains reliable low-oxygen conditions over the storage period.

Inventive Principle:
Principle #5Merging (Combining)

3Stability of the object's composition

If oxygen is not removed quickly in the early period, then the packaging system is simple, but medicine degradation occurs

Engineering Contradiction:
Improvemedicine stabilityVSAvoidtime to achieve low-oxygen state
Core Design Contradiction:
Stability of the object's compositionVSLoss of time

Solution Approach 1:

The moisture-dependent type oxygen scavenger performs preliminary action by rapidly removing oxygen in the early period of storage. This quick oxygen removal establishes a low-oxygen environment quickly, preventing medicine degradation during the critical initial period. The self-reacting type oxygen scavenger then maintains this stable low-oxygen condition over time. This preliminary action principle resolves the contradiction by achieving both fast time to low-oxygen state and long-term medicine stability.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The use of both types of oxygen scavengers ensures quick initial oxygen removal and continuous maintenance of a low-oxygen environment, effectively stabilizing the medicine by preventing degradation and extending its shelf life.

Implementation Method 1

Both a moisture-dependent type oxygen scavenger and a self-reacting type oxygen scavenger are used as the oxygen scavenger

Methodology Applied
Scientific EffectMoisture-dependent oxygen scavenging: Chemical Bonding

Implementation Method 2

Both a moisture-dependent type oxygen scavenger and a self-reacting type oxygen scavenger are used as the oxygen scavenger

Methodology Applied
Scientific EffectSelf-reacting oxygen scavenging: Chemical Bonding

Implementation Method 3

The packaging body is hardly oxygen-permeable

Methodology Applied
Scientific EffectOxygen permeation resistance: Permeation

Data Source

PatentEP3124005B1Packaged drug-filled container
Publication Date: 2019.12.11 TERUMO KK
  • EP3124005B1 patent drawingFigure 1~2
  • EP3124005B1 patent drawingFigure 3~4
  • EP3124005B1 patent drawingFigure 5~6

AI summary

A packaged medicine-filled container (1) has a resin-made medicine-filled container (3) in which a medicine (39) is housed, a sealed packaging body (2) in which the medicine-filled container (3) is housed, and an oxygen scavenger housed inside the packaging body. The packaging body (2) is hardly oxygen-permeable. Both a moisture-dependent type oxygen scavenger (4) and a self-reacting type oxygen scavenger (5) are used as the oxygen scavenger.