Drug Delivery Device Axial Retraction End-of-Content Indication

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Existing drug delivery devices, particularly pen-type injectors, often confuse users with complex end-of-content mechanisms, leading to unexpected cartridge depletion and lack of intuitive indication of remaining medicament levels, which can result in inconvenient or unnecessary cartridge replacements.

Innovation Solution

A drug delivery device design that integrates an end-of-content mechanism through the axial displacement of the cartridge holder into the body, eliminating the need for a separate last dose limiting member, providing a clear and intuitive visual or haptic indication of the cartridge's filling level by altering the device's length.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If a separate last dose limiting member is used to indicate end of content, then the end of content indication is provided, but the device complexity increases

Engineering Contradiction:
Improveend of content indicationVSAvoiddevice complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent combines the end of content indication function with the existing cartridge holder and dose setting mechanism. The cartridge holder itself serves as the indication mechanism through its axial displacement relative to the housing, eliminating the need for a separate last dose limiting member. This merging of functions reduces device complexity while maintaining reliable end of content indication.

Inventive Principle:
Principle #5Merging (Combining)

2Reliability

If a separate last dose limiting member is used, then the end of content mechanism is provided, but the number of parts increases

Engineering Contradiction:
Improveend of content mechanismVSAvoidnumber of parts
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The patent integrates the end of content indication function into the existing cartridge holder component. The cartridge holder's axial displacement relative to the housing during dose setting serves as the visual indication mechanism, eliminating the need for additional separate parts. This reduces the total number of components while maintaining the end of content mechanism's reliability.

Inventive Principle:
Principle #5Merging (Combining)

3Loss of information

If the cartridge holder is fixed in position, then the structure is simple, but the filling level indication is not provided

Engineering Contradiction:
Improvefilling level indicationVSAvoiddevice complexity
Core Design Contradiction:
Loss of informationVSDevice complexity

Solution Approach 1:

The patent makes the cartridge holder dynamically movable in the axial direction during dose setting operations. This axial displacement of the cartridge holder relative to the housing provides real-time visual feedback on the filling level. The dynamic positioning of the cartridge holder allows users to intuitively assess remaining medicament without adding complex indication mechanisms.

Inventive Principle:
Principle #15Dynamics

Data Source

PatentUS10420893B2Drug delivery device
Publication Date: 2019.09.24 SANOFI SYNTHELABO INC
  • US10420893B2 patent drawing
  • US10420893B2 patent drawing
  • US10420893B2 patent drawing

AI summary

A drug delivery device for dispensing of a dose of a medicament includes an elongated body extending in an axial direction, a cartridge holder to accommodate a cartridge at least partially filled with the medicament and having an axially displaceable piston, and a piston rod to operably engage with the piston of the cartridge to displace the piston in axial distal direction. The drug delivery device further includes a coupling member connected with the cartridge holder and being axially displaceably arranged in the body for retracting the cartridge holder into the body during setting of a dose.