Dry Eye Forecast System Using Preliminary Action and Dynamics

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Solution Overview

Problem

Current treatments for dry eye disease lack personalized recommendations for stimulus delivery, failing to effectively address the progressive nature of the condition and its environmental and patient-specific factors.

Innovation Solution

A system that determines environmental and patient-specific properties to form a dry eye forecast, which is used to select a tailored treatment recommendation, including stimulus delivery parameters such as duration and timing, to reduce symptoms and prevent future occurrences.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If electrical stimulation is applied to treat dry eye disease, then tear production is increased, but treatment intensity and energy consumption increase

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidenergy consumption
Core Design Contradiction:
ReliabilityVSUse of energy by moving object

Solution Approach 1:

The system performs preliminary assessment of dry eye severity and environmental conditions before delivering stimulation. By evaluating multiple properties (tear film stability, corneal sensitivity, environmental humidity, temperature) in advance, the system determines the optimal stimulation parameters needed, avoiding unnecessary high-intensity treatment and reducing energy consumption while maintaining effectiveness.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The stimulation parameters are dynamically adjusted based on real-time assessment of dry eye conditions and environmental factors. The system modifies stimulation intensity, duration, and frequency according to the calculated dry eye forecast, ensuring treatment effectiveness while minimizing energy consumption by applying only the necessary stimulation level.

Inventive Principle:
Principle #15Dynamics

2Reliability

If personalized treatment recommendations are implemented, then treatment effectiveness is improved, but system complexity increases

Engineering Contradiction:
Improvetreatment effectivenessVSAvoidsystem complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system segments the treatment approach into distinct functional modules: environmental sensing, property assessment, dry eye forecasting, and treatment recommendation generation. Each module handles a specific aspect of the personalized treatment process, making the overall complex system manageable and maintainable while delivering comprehensive personalized care.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The system introduces a computational model (dry eye forecast) as an intermediary that processes multiple input properties and translates them into treatment recommendations. This intermediary layer simplifies the relationship between complex input data and treatment decisions, enabling personalized treatment without requiring direct complex interactions between all system components.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Use of energy by moving object

If treatment is delayed until symptoms worsen, then treatment intensity can be reduced, but disease progression continues

Engineering Contradiction:
Improvetreatment intensityVSAvoiddisease management
Core Design Contradiction:
Use of energy by moving objectVSReliability

Solution Approach 1:

The system performs preliminary forecasting of dry eye progression based on current conditions and historical data. By predicting future symptom severity, the system enables proactive treatment initiation before symptoms worsen significantly, allowing for lower intensity treatment that is more effective at preventing progression rather than managing advanced disease.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The system continuously monitors environmental conditions and patient symptoms, using this feedback to update the dry eye forecast and adjust treatment recommendations. This closed-loop feedback mechanism ensures treatment intensity is optimized based on actual disease progression, preventing both overtreatment and undertreatment while managing disease effectively.

Inventive Principle:
Principle #23Feedback

Data Source

PatentUS10610095B2Apparatus and method for dry eye forecast and treatment recommendation
Publication Date: 2020.04.07 OCULEVE INC
  • US10610095B2 patent drawing
  • US10610095B2 patent drawing
  • US10610095B2 patent drawing

AI summary

Generally, a machine may include a processor and a memory connected to the processor, where the memory stores instructions executed by the processor to determine first and second properties related to dry eye symptoms of a patient. The properties may be used to form a dry eye forecast. A treatment recommendation may be selected based at least in part upon the dry eye forecast. The treatment recommendation may be supplied to a device.