Dry Powder Plant Extract Formulation Without Inert Carriers

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Solution Overview

Problem

Current plant extract formulations often require inert carriers or excipients, which dilute the potency and add non-plant material, making them unsuitable for organic products and limiting their therapeutic and cosmetic effectiveness.

Innovation Solution

A method involving solvent extraction followed by mixing the plant extract with a dry powdered form of the same or similar plant material to absorb residual moisture, creating a pure, dry powder formulation without inert carriers, allowing for standardized phyto-chemical levels and improved flowability.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of manufacture

If inert carriers or excipients are added to plant extracts to improve flowability and processing, then ease of manufacture is improved, but purity of plant material deteriorates

Engineering Contradiction:
ImproveflowabilityVSAvoidpurity
Core Design Contradiction:
Ease of manufactureVSQuantity of substance

Solution Approach 1:

The invention changes the physical state parameter of the plant extract from liquid to dry powder form. By removing solvent and drying the extract, the natural flowability and free-flowing properties are restored without requiring any inert carriers or excipients, thus maintaining 100% plant purity while achieving good manufacturability

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention extracts and removes the solvent component from the plant extract, separating it from the active plant constituents. This extraction of the solvent leaves behind a pure dry powder containing only plant material, eliminating the need for additional inert carriers

Inventive Principle:
Principle #2Taking out (Extraction)

2Manufacturing precision

If inert carriers are used to standardize plant extracts, then manufacturing precision is improved, but potency of the extract deteriorates

Engineering Contradiction:
ImprovestandardisationVSAvoidpotency
Core Design Contradiction:
Manufacturing precisionVSQuantity of substance

Solution Approach 1:

The invention standardizes the product by controlling the dry powder to plant extract ratio, rather than adding inert carriers. The standardization is achieved through precise measurement and mixing ratios of the dry powder and liquid extract, maintaining full potency while achieving consistent dosing

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The invention creates a composite formulation consisting of two active components: dry powdered plant material and liquid plant extract. Both components contribute therapeutic value, unlike conventional approaches where inert carriers add no activity. The composite maintains full potency while enabling standardization

Inventive Principle:
Principle #40Composite materials

3Quantity of substance

If solvent extraction is used to concentrate active ingredients, then concentration of active constituents is improved, but the product becomes a sludge requiring excipients, worsening ease of operation

Engineering Contradiction:
ImproveconcentrationVSAvoidprocessability
Core Design Contradiction:
Quantity of substanceVSEase of operation

Solution Approach 1:

The invention utilizes phase transition by removing the solvent through evaporation or other separation methods, transforming the liquid extract into a dry powder state. This phase change eliminates the sludge consistency and restores free-flowing properties, making the concentrated extract easy to handle and process without requiring excipients

Inventive Principle:
Principle #36Phase transitions

Solution Approach 2:

The invention replaces the need for mechanical mixing with inert carriers by using a drying process. Instead of mechanically combining extract with excipients to achieve flowability, the thermal or physical removal of solvent directly produces a free-flowing dry powder

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach results in a pure plant extract formulation that maintains the full range of biological activities, is free from non-plant additives, and can be easily processed into various forms like tablets or capsules, enhancing potency and usability in medicinal and cosmetic applications.

Implementation Method 1

mixing the plant extract with a plant or part of a plant in dry powder form in an amount capable of absorbing residual moisture in the plant extract

Methodology Applied
Scientific EffectAbsorption: Absorption (physical)

Data Source

PatentEP2205254A1Method of producing plant extract formulations
Publication Date: 2010.07.14 QUINN PHARMA

AI summary

The present invention provides a method for the production of a dry powder, pure plant extract formulation, comprising extracting a plant or part of a plant with a solvent extraction step, then mixing the resulting plant extract with a plant or part of a plant in dry powder form in an amount capable of absorbing residual moisture in the plant xtract so as to provide a dry powder pure plant extract formulation. The present invention also provides for a formulation made by the said method and the use of such formulations from particular plant sources in treating a variety of disorders.