Dry Thawing Assembly With Agitation for Uniform Biofluid Heating

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Solution Overview

Problem

Existing methods for thawing biological substances, such as plasma and blood, often result in inconsistent temperature control, leading to risks of hypothermia or protein denaturation due to underheating or overheating, which can endanger patients.

Innovation Solution

A dry thawing device with multiple heating assemblies and an agitation mechanism that dynamically controls heat based on temperature measurements, ensuring consistent thawing by pivoting and sliding configurations to evenly distribute heat and monitor temperature.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional thawing methods are used, then the biological substance can be thawed, but the temperature control is inconsistent leading to underheating or overheating

Engineering Contradiction:
Improvetemperature control consistencyVSAvoidpatient harm from underheating or overheating
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent implements a feedback control system using temperature sensors that continuously monitor the biological substance temperature and adjust heating element power accordingly. The controller receives temperature data and modulates heating to maintain the substance within a safe temperature range, preventing both underheating and overheating conditions that could harm patients.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The heating system transitions from static traditional methods to dynamic control where heating power is continuously adjusted based on real-time temperature measurements. The system adapts heating intensity throughout the thawing process, increasing power when temperature is low and reducing power when temperature approaches the target range, ensuring consistent and safe thawing.

Inventive Principle:
Principle #15Dynamics

2Productivity

If heating power is increased to speed up thawing, then productivity improves, but the risk of overheating and protein denaturation increases

Engineering Contradiction:
Improvethawing speedVSAvoidprotein denaturation from overheating
Core Design Contradiction:
ProductivityVSObject-affected harmful factors

Solution Approach 1:

The feedback control system allows high heating power to be applied during early thawing stages when the biological substance is still cold, maximizing thawing speed. As the substance approaches the target temperature, the controller automatically reduces power to prevent overheating and protein denaturation, thus achieving both fast thawing and temperature safety.

Inventive Principle:
Principle #23Feedback

Solution Approach 2:

The heating system employs periodic cycles of high-power heating followed by lower-power maintenance heating. During initial phases, intense heating rapidly raises temperature to improve productivity. As the substance nears the desired temperature range, heating transitions to periodic or reduced-power mode to prevent thermal runaway and protein damage, balancing speed with safety.

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The device provides precise temperature control, reducing the risk of patient harm by ensuring uniform thawing and maintaining the quality of biological substances.

Implementation Method 1

a first heating assembly coupled to the chamber frame. The first heating assembly has a heater configured to be in thermal communication with an enclosed biological substance that is received within the chamber frame

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Implementation Method 2

a second heating assembly can be mounted on the chamber door... the second heating assembly can have a heater that, when the chamber door is in a closed position, is configured to be in thermal communication with an enclosed biological substance

Methodology Applied
Scientific EffectThermal conduction: Conduction (thermal)

Implementation Method 3

an agitation device mounted within the chamber frame and configured to cause the first heating assembly to pivot about a pivot axis relative to the chamber frame such that the first heating assembly can agitate an enclosed biological substance

Methodology Applied
Scientific EffectMechanical motion:

Data Source

PatentUS20260104334A1Thawing biological substances
Publication Date: 2026.04.16 FREMON SCIENTIFIC INC
  • US20260104334A1 patent drawing
  • US20260104334A1 patent drawing
  • US20260104334A1 patent drawing

AI summary

Dry thawing systems and devices for thawing biological substances are provided herein. Methods for thawing biological substances are also provided.