Regional Digital Subtraction Angiography Mask Weighting

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Solution Overview

Problem

Digital subtraction angiography (DSA) and roadmapping techniques in x-ray imaging systems often lead to the loss of anatomical landmarks, which can delay diagnostics and error in the placement of interventional devices due to the removal of bony structures.

Innovation Solution

A method is provided where a mask is generated from a set of mask images, and applied to acquired image data with different weighting inside and outside a region of interest (ROI), allowing for dynamic adjustment of subtraction levels to visualize both vasculature and landmarks within the same image frame.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Illumination intensity

If image subtraction techniques are applied to remove unwanted bony structures, then visibility of vasculature is enhanced, but anatomical landmarks are lost

Engineering Contradiction:
Improvevisibility of vasculatureVSAvoidanatomical landmarks
Core Design Contradiction:
Illumination intensityVSLoss of information

Solution Approach 1:

The patent applies different subtraction weights to different regions of the image. A first weight is applied within the region of interest (ROI) to enhance vasculature visibility, while a second weight is applied outside the ROI to preserve anatomical landmarks. This local differentiation resolves the contradiction by allowing full subtraction where needed (inside ROI) and partial or no subtraction where landmarks are needed (outside ROI).

Inventive Principle:
Principle #3Local quality

2Measurement precision

If full mask subtraction is applied to enhance vasculature visualization, then diagnostic accuracy for vascular flow is improved, but placement accuracy of interventional devices deteriorates

Engineering Contradiction:
Improvediagnostic accuracy for vascular flowVSAvoidplacement accuracy of interventional devices
Core Design Contradiction:
Measurement precisionVSManufacturing precision

Solution Approach 1:

The system applies a first weight within the ROI that enables accurate vascular flow diagnostics, while applying a second weight outside the ROI that preserves anatomical landmarks for accurate device placement. This local quality differentiation allows both diagnostic accuracy and placement precision to be maintained in their respective regions.

Inventive Principle:
Principle #3Local quality

3Loss of information

If regional weighting of mask is applied to preserve landmarks outside ROI, then anatomical reference is maintained, but vasculature visibility inside ROI is reduced

Engineering Contradiction:
Improveanatomical landmarks outside ROIVSAvoidvasculature visibility inside ROI
Core Design Contradiction:
Loss of informationVSIllumination intensity

Solution Approach 1:

The patent implements local quality by applying a first weight specifically within the ROI to maximize vasculature visibility, and a second weight outside the ROI to preserve anatomical landmarks. This regional differentiation ensures that each area receives the appropriate level of subtraction for its specific diagnostic needs.

Inventive Principle:
Principle #3Local quality

4Adaptability or versatility

If dynamic adjustment of subtraction levels is enabled, then user flexibility in visualizing both vasculature and landmarks is improved, but system complexity increases

Engineering Contradiction:
Improveuser flexibility in visualizationVSAvoidsystem complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system implements dynamics by allowing real-time adjustment of the first and second weights applied to different regions. Users can dynamically modify the subtraction levels within and outside the ROI based on diagnostic needs, providing flexibility without requiring complex manual processing of multiple images.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system segments the image into two distinct regions (inside and outside ROI) and applies independent weighting to each segment. This segmentation simplifies the complexity by creating clear, manageable regions with distinct processing rules, making the system easier to control and adjust.

Inventive Principle:
Principle #1Segmentation

Data Source

PatentEP3300018B1Systems and methods for generating subtracted images
Publication Date: 2020.07.15 GENERAL ELECTRIC CO
  • EP3300018B1 patent drawingFigure 1~2
  • EP3300018B1 patent drawingFigure 3A
  • EP3300018B1 patent drawingFigure 3B

AI summary

Methods and systems are provided for generating regional digital subtraction angiography (DSA) images and roadmap images with landmarks. In one embodiment, a method comprises generating a mask from a set of mask images of an anatomy of a subject 710, and generating a masked image by applying the mask to acquired image data of the anatomy of the subject, including weighting the mask differently inside a region of interest (ROI) of the image than outside the ROI, the weighting inside ROI independent of the weighting outside the ROI 720. In this way, a user may be able to adjust a relative magnitude of subtraction inside and outside the ROI, and thus be able to visualize both vasculature and landmarks within the same image frame.