Dual-Chamber Liquid Separation Kit for Low-Contamination PRP Handling
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Solution Overview
Problem
Existing liquid sampling and separation processes, such as those used for platelet-rich plasma (PRP), are prone to contamination and require multiple tools, increasing the risk of human error and sample misplacement, especially with large volumes, which can lead to safety issues and reduced purity.
Innovation Solution
A liquids separation kit that integrates blood sampling, separation, and storage in a single container, using a container body with two compartments and a control module to perform multiple separation processes, including centrifugation and vibration, while minimizing tool exchange and potential contamination.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If multiple tools are used for blood sampling, separation and storage, then the separation process can be performed, but the risk of contamination and human error increases
Solution Approach 1:
The patent combines blood sampling, separation and storage functions into a single integrated device. The container body serves as both the sampling vessel and separation chamber, eliminating the need for multiple separate tools. This merging of functions directly reduces contamination risk and human error while maintaining separation capability.
Solution Approach 2:
The device is designed as a multi-functional system where the container body performs multiple roles: collecting blood samples, facilitating separation through centrifugation, and storing separated components. This universal design allows one device to replace multiple specialized tools, thereby improving reliability without sacrificing functionality.
2Reliability
If multiple tools are exchanged during separation process, then separation can be achieved, but the risk of sample misplacement and contamination increases
Solution Approach 1:
By integrating all separation functions within a single container body, the patent eliminates the need to exchange multiple tools during the separation process. The unified structure ensures samples remain in one location throughout, preventing misplacement and contamination while simplifying the operational workflow.
3Reliability
If a single container is used for all separation steps, then contamination risk is reduced, but the device must perform multiple functions
Solution Approach 1:
The container body is divided into multiple compartments (first compartment and second compartment) that can be independently accessed. This segmentation allows different separation steps to be performed in isolated areas, preventing cross-contamination while maintaining the benefits of a single-container design. The compartments provide functional organization without compromising contamination resistance.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Ensures high-concentration component separation with reduced contamination risk by allowing simultaneous handling of multiple separation steps within a single container, enhancing safety and efficiency in obtaining components like PRP.
Implementation Method 1
The piston is disposed in the first room and is movable therein, so as to produce a suction force or a pressing force at the connecting end of the first room
Implementation Method 2
The control unit is coupled to the tubes for conducting or stopping liquids flows within the tubes by operating the control unit
Implementation Method 3
PRP is the concentrated platelets with some other constituents of blood, prepared by utilizing separation kits to perform the separation process with constant speed centrifugation based on the different sedimentation coefficients of the constituents in the whole blood sample
Implementation Method 4
The connecting piece has a first end and a second end. The first end is connecting to the connecting end of the first room; wherein partial of the connecting piece is exposed in between the first and second rooms
Data Source
AI summary
The present invention provides a liquids separation kit that has a control unit on a container body to selectively control the separation or conduction between a first room and outside the container body and between the first room and a second room, thereby easily obtaining a first component which is perhaps highly concentrated after separation process.