Dual-Detector Tissue Tracking for Radiation Therapy Beams

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Solution Overview

Problem

Current radiation therapy systems face challenges in accurately tracking tumors using beam's-eye-view imaging, particularly when fiducial markers are outside the field-of-view defined by the multi-leaf collimator, leading to difficulties in delivering precise radiation treatment.

Innovation Solution

A radiation therapy system with a dual-detector imaging system, where a first detector acquires imaging data within the attenuated periphery of the radiation therapy beam and a second detector, with higher gain, tracks the fiducial marker outside the attenuated periphery, allowing for improved tissue tracking regardless of the marker's position relative to the beam.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If beam's-eye-view imaging with a single detector is used, then the system is simple, but it cannot track fiducial markers outside the field-of-view

Engineering Contradiction:
Improvetracking capabilityVSAvoiddetector system
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The imaging system is divided into two separate detectors: a first detector positioned to receive radiation within the attenuated periphery and a second detector positioned to receive radiation outside the attenuated periphery. Each detector is optimized for its specific region, allowing the system to track fiducial markers regardless of their position relative to the beam center, thereby resolving the contradiction between tracking versatility and system simplicity.

Inventive Principle:
Principle #1Segmentation

2Measurement precision

If a single detector with high gain is used, then tracking sensitivity is improved, but dose violations increase due to saturation

Engineering Contradiction:
Improvetracking accuracyVSAvoiddose delivery accuracy
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The detection function is segmented between two detectors with different gain characteristics. The first detector uses a lower gain optimized for measuring radiation intensity within the beam periphery to avoid saturation and ensure accurate dose delivery. The second detector uses a higher gain optimized for detecting fiducial markers outside the beam periphery. This segmentation allows each detector to operate within its optimal dynamic range, simultaneously achieving tracking accuracy and dose delivery reliability.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The computing device acts as an intermediary that receives imaging data from both detectors and processes the information to determine fiducial marker positions. It combines the low-gain intensity measurements from the first detector with the high-gain position measurements from the second detector, mediating between the conflicting requirements of dose accuracy and tracking sensitivity to produce reliable combined results.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If the field-of-view is expanded to include all markers, then tracking coverage is improved, but the beam's-eye-view imaging quality deteriorates

Engineering Contradiction:
Improvefield coverageVSAvoidimaging quality
Core Design Contradiction:
Adaptability or versatilityVSMeasurement precision

Solution Approach 1:

The imaging system segments the field-of-view into two distinct regions: an inner region within the attenuated periphery handled by the first detector optimized for beam intensity measurement, and an outer region outside the periphery handled by the second detector optimized for fiducial marker detection. This spatial segmentation allows each detector to maintain optimal imaging quality for its designated region while collectively providing expanded field coverage.

Inventive Principle:
Principle #1Segmentation

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables more accurate and efficient tumor tracking, reducing the need for re-planning and minimizing dose violations, while allowing for real-time monitoring and adjustment of the radiation beam to ensure precise targeting.

Implementation Method 1

the second radiation detector includes a layer of scintillating glass

Methodology Applied
Scientific EffectScintillation: Scintillation

Implementation Method 2

the first radiation detector includes a gadolinium oxysulfide (GOS) detector

Methodology Applied
Scientific EffectPhotoluminescence: Photoluminescence

Data Source

PatentUS11998762B2Systems and methods for tissue tracking with radiation therapy beams
Publication Date: 2024.06.04 THE BRIGHAM & WOMEN S HOSPITAL INC
  • US11998762B2 patent drawing
  • US11998762B2 patent drawing
  • US11998762B2 patent drawing

AI summary

Some aspects of the disclosure provide a radiation therapy system. The system can include a radiation source configured to emit a radiation therapy beam, a collimator positioned to attenuate at least a periphery of the radiation therapy beam, a radiation fiducial marker configured to be coupled to a patient, and a first radiation detector and a second radiation detector configured to receive the radiation therapy beam after passing through a patient. The system also includes a computer configured to determine a position of the radiation fiducial marker using information from the first detector and the second detector.