Bioresorbable Anchor With Dual-Layer Resorption Control
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Solution Overview
Problem
Existing vascular closure devices face challenges in achieving the desired initial strength and resorption rate for anchors used in sealing tissue punctures, as materials that provide bioresorbability may not offer sufficient initial strength, and vice versa, with limited control over the resorption process.
Innovation Solution
The use of a dual-layer anchor system comprising an inner and outer bioresorbable material, where the outer layer is overmolded or coated onto the inner layer, allowing for tailored resorption rates and enhanced strength by varying the hydrophilicity and material properties, such as using PEG hydrogel for the inner anchor and a softer outer material for delayed resorption.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Duration of action of stationary object
If a bioresorbable material is used for the anchor, then the anchor can be resorbed by the body within a desired period of time, but the initial strength of the anchor is insufficient
Solution Approach 1:
The patent applies composite materials by combining two different bioresorbable materials with distinct resorption rates. The first material provides rapid initial resorption while the second material maintains structural integrity over a longer period, creating a composite anchor that simultaneously achieves both rapid resorption capability and sustained initial strength requirements
Solution Approach 2:
The anchor is segmented into two distinct material components with different resorption characteristics. This segmentation allows each material to perform its specific function - one material resorbs quickly to clear the site while the other maintains strength - thereby resolving the contradiction between rapid resorption and initial strength
2Strength
If a material with high strength is used for the anchor, then the anchor can fulfill the strength requirement, but the resorption rate is too slow
Solution Approach 1:
The patent uses composite materials where the second material provides the necessary high strength and structural support, while the first material ensures adequate resorption rate. The combination allows the anchor to maintain strength requirements while achieving the desired resorption timeline through the synergistic interaction of the two materials
3Duration of action of stationary object
If greater control over the resorption rate is achieved, then the healing process can be optimized, but the material selection and design complexity increases
Solution Approach 1:
The patent applies parameter changes by selecting materials with specifically tuned resorption rate parameters. By choosing two materials with complementary resorption characteristics, the design achieves controlled resorption timing without requiring complex mechanical structures or additional control mechanisms, thus managing complexity while optimizing the healing process
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach enables the anchor to maintain initial strength during the healing process while resorbing at a controlled rate, ensuring effective sealing and healing without premature weakening or bending, thus improving the efficacy of vascular closure.
Implementation Method 1
The inner anchor material, which tends to swell and undergo hydrolysis at a faster rate than the outer anchor material
Implementation Method 2
The inner anchor is made of a bioresorbable material with a more rapid bioresorption rate than the outer anchor material
Implementation Method 3
The outer anchor material is less hydrophilic than the inner anchor material
Data Source
AI summary
A bioresorbable anchor for deployment in a live body, in one embodiment the anchor comprises an inner anchor made of a first bioresorbable material and an outer anchor made of a second bioresorbable material, wherein the outer anchor envelops the inner anchor. In another embodiment, the anchor comprises a base anchor made of a first bioresorbable material and a second bioresorbable material overlays at least a portion of the base anchor. The first bioresorbable material has a faster resorption rate than the second bioresorbable material. Further, the second bioresorbable material can provide additional strength to the anchor structure. A tissue puncture closure device comprising a filament extending from a first end of the closure device to a second end of the closure device; an anchor comprising a plurality of bioresorbable materials; a sealing plug slidingly attached to the filament adjacent to the anchor; and a tamping assembly.