Dual-Layer Reference Fluid Bag for Gas-Tight Sensor Calibration

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Solution Overview

Problem

Existing sealed bags for reference fluids used in sensor calibration and quality control face issues with parasitic hydrogen generation due to corrosion of aluminum gas diffusion barriers, which interfere with electrochemical sensor measurements, particularly in multiple sensor devices requiring tight gas tightness and sensitivity to hydrogen.

Innovation Solution

A sealed bag design with a dual-layered material structure, where the access port is sealed by a cover made of a second layered material resistant to oxidation by the reference fluid, preventing parasitic hydrogen generation while maintaining gas tightness, using materials like aluminum oxide or silicon oxide for the gas barrier layers.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If aluminum gas diffusion barrier layers are used in sealed bags, then gas tightness is improved, but parasitic hydrogen generation occurs due to corrosion which interferes with electrochemical sensor measurements

Engineering Contradiction:
Improvegas tightnessVSAvoidparasitic hydrogen generation
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The bag structure is segmented into multiple functional layers: an inner layer in contact with reference fluid, an intermediate corrosion-resistant layer (e.g., aluminum oxide or silicon oxide) that prevents hydrogen generation, and an outer aluminum gas diffusion barrier layer for tightness. This segmentation allows each layer to perform its specific function without interfering with others.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

A corrosion-resistant intermediate layer (aluminum oxide or silicon oxide) is introduced between the reference fluid and the aluminum gas diffusion barrier layer. This intermediary layer acts as a protective barrier that prevents direct contact between the aluminum and the reference fluid, thereby eliminating parasitic hydrogen generation while maintaining the gas tightness function of the aluminum layer.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-generated harmful factors

If aluminum oxide or silicon oxide layers are used instead of aluminum, then parasitic hydrogen generation is prevented, but gas diffusion barrier performance may be compromised

Engineering Contradiction:
Improveparasitic hydrogen generationVSAvoidgas diffusion barrier performance
Core Design Contradiction:
Object-generated harmful factorsVSReliability

Solution Approach 1:

The bag employs a composite material structure combining different materials with complementary properties: corrosion-resistant materials (aluminum oxide or silicon oxide) for hydrogen prevention and aluminum for superior gas diffusion barrier performance. The composite structure leverages the strengths of each material while mitigating their individual weaknesses.

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The gas barrier function is segmented between layers: the corrosion-resistant intermediate layer provides chemical stability and prevents hydrogen generation, while the outer aluminum layer provides the primary gas diffusion barrier performance. This functional segmentation allows optimization of each layer for its specific purpose.

Inventive Principle:
Principle #1Segmentation

3Adaptability or versatility

If multiple sensor devices are used for simultaneous measurement of multiple parameters, then comprehensive patient monitoring is improved, but requirements for calibration and quality control become more restrictive

Engineering Contradiction:
Improvecomprehensive parameter measurementVSAvoidcalibration and quality control tolerances
Core Design Contradiction:
Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The sealed bag with corrosion-resistant intermediate layer serves multiple functions: it maintains gas tightness for accurate reference fluid composition, prevents parasitic hydrogen generation that would interfere with any electrochemical sensor, and provides a universal solution for calibrating and quality controlling multiple different sensor types simultaneously.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The invention changes the chemical composition parameters of the bag materials by introducing corrosion-resistant intermediate layers, which fundamentally alters the electrochemical environment to eliminate hydrogen generation. This parameter change ensures that reference fluids maintain their calibrated concentrations without contamination, meeting the restrictive tolerances required for multi-sensor calibration.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution effectively reduces parasitic hydrogen generation and enhances gas tightness, ensuring reliable calibration and quality control procedures for electrochemical sensors, particularly in multiple sensor devices.

Implementation Method 1

a gas barrier layer made of aluminium arranged between the inner and outer layers

Methodology Applied
Scientific EffectGas diffusion barrier: Diffusion Barrier

Implementation Method 2

pristine aluminium when exposed to an aqueous solution will undergo a corrosion reaction thereby producing hydrogen released into the reference fluid

Methodology Applied
Scientific EffectCorrosion reaction: Oxidation

Data Source

PatentUS12447472B2Bag containing a reference fluid
Publication Date: 2025.10.21 RADIOMETER AS
  • US12447472B2 patent drawing
  • US12447472B2 patent drawing
  • US12447472B2 patent drawing

AI summary

The invention relates to a sealed bag containing a reference fluid for the calibration or quality control of a sensor element for measuring body fluid parameters, the bag comprising peripheral walls of a first layered material. The bag further comprises an access port formed by an opening in the first layered material, wherein the opening is sealed by a cover of a second layered material, wherein the second layered material is more resistant to oxidation by the reference fluid than the first layered material.