Dual-Mode Urine Analyzer Using Dynamic Reagent Mixing

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Solution Overview

Problem

Conventional urine analyzers are limited to analyzing only urine samples and require separate analyzers for body fluids, leading to inefficiencies in medical settings where both types of samples need to be examined.

Innovation Solution

A urine analyzer capable of operating in both urine and body fluid measurement modes, using a specimen preparing section to mix samples with specific reagents and a detecting section to analyze red blood cells and bacteria in urine, and white blood cells and nucleated cells in body fluids, utilizing a single device.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If a conventional urine analyzer is used, then urine samples can be analyzed accurately, but body fluid samples cannot be analyzed (requiring separate analyzers)

Engineering Contradiction:
Improvesample type compatibilityVSAvoidanalyzer system configuration
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The analyzer is designed with multiple measurement modes (urine measurement mode and body fluid measurement mode) that can be switched via a mode setting unit. The same analyzer hardware processes both urine and body fluid samples by adjusting operational parameters, eliminating the need for separate dedicated analyzers for different sample types.

Inventive Principle:
Principle #6Universality (Multi-functionality)

2Reliability

If separate analyzers are installed for urine and body fluid analysis, then each sample type can be analyzed with dedicated equipment, but the number of devices and examination rooms increases

Engineering Contradiction:
Improvemeasurement accuracyVSAvoidexamination room efficiency
Core Design Contradiction:
ReliabilityVSProductivity

Solution Approach 1:

A single analyzer performs both urine and body fluid analysis functions, allowing one examination room to handle multiple sample types. This consolidates equipment usage and improves productivity without compromising measurement accuracy through mode-specific optimization.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The analyzer dynamically adjusts its operational parameters based on the selected measurement mode. Different measurement conditions are applied for urine versus body fluid samples, allowing the system to optimize performance for each sample type while using the same physical hardware.

Inventive Principle:
Principle #15Dynamics

3Productivity

If a single analyzer handles multiple sample types, then device utilization improves, but measurement conditions must be adjusted for different samples

Engineering Contradiction:
Improveanalyzer utilization rateVSAvoidmeasurement condition management
Core Design Contradiction:
ProductivityVSDevice complexity

Solution Approach 1:

The system employs a mode setting unit that dynamically changes measurement conditions based on the selected mode (urine or body fluid). This automated parameter adjustment simplifies the management of different measurement conditions while maintaining high analyzer utilization across multiple sample types.

Inventive Principle:
Principle #15Dynamics

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables accurate and efficient analysis of both urine and body fluid samples using a single analyzer, reducing the need for multiple devices and improving workflow in medical settings.

Implementation Method 1

a second reagent having a hemolytic effect

Methodology Applied
Scientific EffectHemolysis:

Implementation Method 2

analyzed by optically measuring the measurement specimen

Methodology Applied
Scientific EffectOptical measurement:

Data Source

PatentUS9746461B2Urine sample analyzer and sample analyzing method
Publication Date: 2017.08.29 SYSMEX CORP
  • US9746461B2 patent drawing
  • US9746461B2 patent drawing
  • US9746461B2 patent drawing

AI summary

A urine analyzer capable of operating in a urine measurement mode and a body fluid measurement mode, the urine analyzer includes a specimen preparing section configured to prepare a measurement specimen and a detecting section configured to derive signals of particles in the measurement specimen supplied from the specimen preparing section. A computer and a memory including programs on a computer-readable medium that enable the computer to execute operations to control the specimen preparing section and the detecting section in the urine measurement mode and in the body fluid measurement mode.