Dual-Nozzle Assembly Structure to Prevent Magnetic Particle Suction
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Solution Overview
Problem
Existing nozzle assemblies for immunoreactions, particularly those integrating suction and jetting nozzles, suffer from increased cross-sectional ratio and proximity to magnetically collected magnetic particles, leading to erroneous suction during BF separation.
Innovation Solution
A nozzle assembly with integrated nozzles having a recess portion filled with a filling member, maintaining an oval cross-section and uncovered end parts, made of metal with a fluorine-based coating, to prevent capillary action and liquid adhesion.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Productivity
If two nozzles are integrated with a cover, then BF separation efficiency is improved, but the cross-sectional ratio increases and distance to magnetic particles decreases causing erroneous suction
Solution Approach 1:
The patent removes the cover that was previously used to protect the integrated nozzles. By extracting this covering structure, the outer periphery of the nozzle assembly becomes smaller, reducing the cross-sectional ratio and increasing the distance to magnetically collected particles, thereby preventing erroneous suction while maintaining the integrated nozzle configuration for efficient BF separation
Solution Approach 2:
The patent segments the nozzle assembly into distinct functional components: integrated nozzles for liquid handling and magnetic particles collection, without a unified cover. This segmentation allows the nozzle outer periphery to be minimized independently, reducing the risk of magnetic particle suction while preserving the dual-nozzle integration for efficient BF separation
2Ease of operation
If nozzles are integrated, then operation efficiency is improved, but cross-sectional ratio increases making magnetic particle suction more likely
Solution Approach 1:
The patent extracts the cover structure from the integrated nozzle assembly, removing the source of the harmful effect (large outer periphery) while preserving the beneficial integration of nozzles for efficient operation. This extraction reduces the cross-sectional footprint without compromising operational efficiency
Solution Approach 2:
The patent applies local quality by having nozzles integrated only where functionally necessary for efficient operation, rather than enclosing the entire assembly. The integrated nozzles maintain operational efficiency while the reduced outer periphery minimizes harmful magnetic particle suction effects
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Enhances efficient BF separation by preventing erroneous suction of magnetic particles and reducing measurement inaccuracies in immunoreactions.
Implementation Method 1
preventing capillary action and liquid adhesion
Implementation Method 2
fluorine-based coating
Data Source
AI summary
In a nozzle assembly and an examination apparatus, the nozzle assembly is a nozzle assembly in which two nozzles with circular cross sections are integrated in a state of being brought into contact with each other, in which a recess portion that is generated in a part of an outer periphery of the two nozzles in contact with each other and that has a valley at a contact portion where the nozzles are brought into contact with each other is flattened by being filled with a filling member, and a part of the outer periphery other than the recess portion, the part including both end parts of the outer periphery in a maximum diameter direction, is not covered by the filling member.