Dual-Opening Blister Pack for Controlled Dose Dispensing

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Solution Overview

Problem

Conventional blister packs for pharmaceuticals suffer from irreversible destruction upon use, uncontrolled release of contents, and difficulty in targeted administration due to the brittle release liner and uncontrolled pressure buildup.

Innovation Solution

A blister pack design with a second opening sealed by a removable sealing film, adhesive strip, or temperature-sensitive film, allowing controlled release through heating or pressure application, enabling targeted dispensing of contents.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Object-affected harmful factors

If the blister pack is sealed hermetically to protect contents, then protection from environmental influences is improved, but controlled release capability deteriorates

Engineering Contradiction:
Improveprotection from environmental influencesVSAvoidcontrolled release capability
Core Design Contradiction:
Object-affected harmful factorsVSEase of operation

Solution Approach 1:

The blister pack is divided into two separate openings: a first opening sealed by a temperature-resistant first sealing film for hermetic protection during storage, and a second opening sealed by a temperature-sensitive second sealing film for controlled release. This segmentation allows each opening to serve its specific function independently, resolving the contradiction between protection and controlled release.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

Different sealing films with different temperature resistance properties are applied to different locations (openings) of the blister pack. The first sealing film has high temperature resistance for permanent sealing, while the second sealing film has low temperature resistance for controlled opening. This local differentiation of material properties enables both protection and controlled release functions.

Inventive Principle:
Principle #3Local quality

2Device complexity

If pressure buildup is used to release contents, then release mechanism is simplified, but release control and targeting deteriorate

Engineering Contradiction:
Improverelease mechanism simplicityVSAvoidrelease control and targeting
Core Design Contradiction:
Device complexityVSEase of operation

Solution Approach 1:

The second sealing film is designed to change its sealing state based on temperature parameters. At storage temperatures, it maintains a sealed state; when exposed to elevated temperatures (e.g., from a heat source or body heat), it transitions to an open state, allowing controlled release of contents through the second opening without requiring complex pressure buildup mechanisms.

Inventive Principle:
Principle #35Parameter changes

3Ease of operation

If the release liner is made thin for ease of removal, then ease of opening is improved, but structural integrity and control deteriorate

Engineering Contradiction:
Improveease of openingVSAvoidstructural integrity and control
Core Design Contradiction:
Ease of operationVSStrength

Solution Approach 1:

The sealing function is segmented between two separate sealing films instead of relying on a single thin release liner. The first sealing film provides structural integrity for hermetic sealing, while the second sealing film provides controlled opening capability. This eliminates the need for a thin, brittle release liner that compromises structural integrity.

Inventive Principle:
Principle #1Segmentation

4Ease of manufacture

If the blister pack is designed for single use, then manufacturing simplicity is improved, but versatility and repeated administration capability deteriorate

Engineering Contradiction:
Improvemanufacturing simplicityVSAvoidrepeated administration capability
Core Design Contradiction:
Ease of manufactureVSAdaptability or versatility

Solution Approach 1:

The blister pack is designed with two distinct openings serving different functions: the first opening remains permanently sealed for maintaining hermetic protection during storage and transport, while the second opening provides controlled access for repeated administrations. This allows the same package to serve both as a protective container and as a multiple-dose delivery system.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The blister pack structure is designed to perform multiple functions: hermetic protection during storage, controlled release during administration, and repeated access for multiple doses. The presence of two sealed openings with different sealing film properties enables the package to fulfill multiple roles that would otherwise require different packaging solutions.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

Enables targeted and controlled release of pharmaceuticals, protecting the pack from environmental influences and facilitating precise administration.

Implementation Method 1

heating the metering reservoir and the agent contained therein and its sublimation

Methodology Applied
Scientific EffectSublimation: Sublimation

Implementation Method 2

the adhesive strip is a plastic film with an adhesive surface

Methodology Applied
Scientific EffectAdhesion: Adhesive

Implementation Method 3

The second sealing film, sealing strip or adhesive strip is advantageously adhesive, tightly sealing and plastically melting at 60 to 90 °C

Methodology Applied
Scientific EffectMelting: Melting

Data Source

PatentEP4647058A1Blister with second opening
Publication Date: 2025.11.12 BLISTOX GBR
  • EP4647058A1 patent drawingFigure 1
  • EP4647058A1 patent drawingFigure 2~3
  • EP4647058A1 patent drawing

AI summary

The present invention relates to a blister pack (1) for receiving one or more single doses of an agent (2), comprising at least one completely sealed cup (10) forming a dosing reservoir (100) for a single dose and having a circumferential rim (11). The blister pack (1) includes at least one first sealing film (12) that completely seals at least one first opening (101) on the rear side (102) of the at least one cup (10), forming the dosing reservoir (100) which is designed as a cavity containing the agent (2). The blister pack (1) according to the invention is characterized in that the at least one cup (10) has a second opening (104) on its front side (103) in its cup base (105) for dispensing the agent (2), which is completely sealed by means of a second sealing film (13), a sealing strip, or an adhesive strip arranged on the outside (1040) of the opening (104).