Dual-Pump Compounding Manifold for Accurate Low-Volume Mixing
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Solution Overview
Problem
Existing compounding devices face inefficiencies in setup time, downtime during ingredient replacement, and accuracy at small dispensed volumes, while also requiring complex maintenance to maintain aseptic conditions and prevent errors.
Innovation Solution
A compounding device system that includes a micro pump and a macro pump, along with a transfer set featuring a manifold with separate channels for micro and macro lines, which allows for precise control and mixing of fluids, and an intuitive interface for easier operation and maintenance.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Device complexity
If a single pump mechanism is used for both micro and macro fluid delivery, then device complexity is reduced, but measurement precision and delivery accuracy deteriorate
Solution Approach 1:
The patent divides the fluid delivery system into two separate pump mechanisms: a micro pump for precise delivery of small volumes (e.g., additives, vitamins, minerals) and a macro pump for larger volume delivery (e.g., base solutions). This segmentation allows each pump to be optimized for its specific volume range, maintaining high measurement precision while managing device complexity through functional specialization.
2Reliability
If complex maintenance procedures are implemented to maintain aseptic conditions, then reliability improves, but ease of operation deteriorates
Solution Approach 1:
The transfer set is designed as a separate, disposable component that connects the pumps to the fluid containers. This segmentation allows the transfer set to be easily removed and replaced without cleaning or disinfecting the expensive pump mechanisms. The transfer set can be discarded after single use, maintaining aseptic conditions while simplifying operation for the user.
Solution Approach 2:
The transfer set is designed as a disposable component that is inexpensive compared to the pump mechanisms. After use, the entire transfer set is discarded rather than cleaned or sterilized, ensuring aseptic conditions are maintained while eliminating complex maintenance procedures. This approach prioritizes reliability through disposability while maintaining ease of operation.
3Device complexity
If volumetric measurement methods are used, then device complexity is reduced, but measurement precision deteriorates due to multiple affecting factors
Solution Approach 1:
The patent introduces an intermediary measurement system: a load cell that measures the weight of fluid delivered, combined with software that converts weight to volume using the specific gravity of the fluid. This intermediary gravimetric measurement method provides high precision without significantly increasing device complexity, as the load cell and software calculation are straightforward additions to the pump system.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The system operates more efficiently with reduced downtime and improved accuracy at small volumes, while its design promotes easier cleaning and disinfection to maintain aseptic conditions and prevent errors.
Implementation Method 1
Gravimetric devices generally use a peristaltic pump mechanism combined with a weight scale or load cell to measure volume delivered
Implementation Method 2
variances in the pump tubing's material, length, elasticity, and diameter
Implementation Method 3
Gravimetric devices generally use a peristaltic pump mechanism combined with a weight scale or load cell to measure volume delivered. The volume delivered is calculated by dividing the weight delivered by the specific gravity of the ingredient
Data Source
Figure 1
Figure 2A~2B
Figure 3A~3B
AI summary
An exemplary compounding system and method can include two pump heads for simultaneously drawing two different fluids from at least two separate input containers such that the at least two different fluids are mixed and distributed to an output container. The system can include a manifold that maintains separation of certain of the different fluids until after passing by a first pump and a second pump and/or additional pumps. A junction can be placed in the fluid line downstream of the first and second pumps and/or additional pumps such that all or some of the fluids are mixed prior to output to the output container. The method of using the system can include incorporating software that selects various fluids at certain times and sequences to ensure optimum efficiency and safety for the system, and can continue compounding actions even when an input supply container runs out or otherwise fails to supply a particular fluid/material. The method of use also includes connection of a transfer set to a housing in a manner that further ensures optimum efficiency and safety.