Dual Spatial Saturation Pulses for MRI Chemical Shift Compensation

Resolve Bottlenecks,
Find Innovative Solutions
Generate Solutions

Solution Overview

Problem

Traditional spatial saturation pulses in MRI systems are limited by chemical shift displacement, which affects the accuracy of imaging by causing shifts in the suppression of water and fat signals, especially on higher field systems, and are not effectively compensated for, leading to artifacts in imaging.

Innovation Solution

The use of dual spatial saturation pulses with calculated amplitudes and opposite gradient directions is applied before the imaging pulse sequence to compensate for chemical shift displacement, ensuring that the final spatial saturation band is free of such displacement, thereby reducing sensitivity to pulse bandwidth and maintaining image accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If a higher bandwidth RF pulse is utilized to reduce chemical shift displacement, then chemical shift displacement is reduced, but higher maximum B1 is required which limits reusage of existing pulses on higher field systems

Engineering Contradiction:
Improvechemical shift displacement accuracyVSAvoidmaximum B1 requirement
Core Design Contradiction:
Measurement precisionVSPower

Solution Approach 1:

The patent divides a single high-bandwidth saturation pulse into multiple lower-bandwidth pulses applied at different time points. This segmentation allows each individual pulse to operate at lower B1 levels while collectively achieving the desired saturation effect across the frequency spectrum, thereby reducing chemical shift displacement without requiring excessive maximum B1 that would limit reuse on higher field systems.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent employs periodic application of saturation pulses at different frequency offsets rather than a single continuous high-bandwidth pulse. By periodically applying multiple pulses with appropriate timing and frequency distribution, the system achieves comprehensive spectral saturation while keeping individual pulse power levels manageable, enabling reuse on higher field systems with different B1 characteristics.

Inventive Principle:
Principle #19Periodic action

2Device complexity

If traditional single spatial saturation pulse is used, then the imaging process is simple, but chemical shift displacement causes artifacts in imaging

Engineering Contradiction:
Improvepulse sequence complexityVSAvoidchemical shift artifacts
Core Design Contradiction:
Device complexityVSObject-generated harmful factors

Solution Approach 1:

The patent segments the saturation process into multiple pulses with different frequency offsets and timing parameters. This segmentation approach eliminates chemical shift artifacts by ensuring comprehensive saturation across all relevant frequencies, while the modular structure of multiple simple pulses keeps the overall sequence complexity manageable compared to designing a single complex high-bandwidth pulse.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent applies preliminary saturation pulses at specific frequency offsets before the main imaging sequence to pre-compensate for expected chemical shift displacements. This preliminary action ensures that by the time the imaging sequence executes, the saturation bands are properly positioned without artifacts, simplifying the main imaging sequence while eliminating harmful chemical shift effects.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach enables the generation of spatial saturation bands that are less sensitive to chemical shift displacement, improving image quality by maintaining the desired saturation effect and reducing artifacts caused by chemical shift, even in the presence of varying local center frequency offsets.

Implementation Method 1

chemical shift displacement between water and fat

Methodology Applied
Scientific EffectChemical shift:

Implementation Method 2

nuclear magnetic resonance (NMR) signals

Methodology Applied
Scientific EffectMagnetic resonance:

Implementation Method 3

magnetic field gradients (Gx, Gy, and Gz) are employed

Methodology Applied
Scientific EffectMagnetic field gradient:

Implementation Method 4

radio frequency (RF) energy to suppress the MR signal

Methodology Applied
Scientific EffectRadio frequency excitation:

Implementation Method 5

process about it in random order at their characteristic Larmor frequency

Methodology Applied
Scientific EffectLarmor precession:

Data Source

PatentUS11703558B1System and method for utilizing dual spatial saturation pulses to compensate for chemical shift displacement in a spatial saturation band
Publication Date: 2023.07.18 GE PRECISION HEALTHCARE LLC
  • US11703558B1 patent drawing
  • US11703558B1 patent drawing
  • US11703558B1 patent drawing

AI summary

A method to compensate for chemical shift displacement includes, prior to applying an imaging pulse sequence to acquire MRI data of a subject, applying a first saturation pulse within a slice location of an imaging volume of the subject in which the MRI data is to be acquired, wherein the first saturation pulse results in a first chemical shift displacement between water and fat in a first spatial saturation band. The method also includes, prior to applying the imaging pulse sequence, subsequently applying a second saturation pulse within the slice location, wherein the second saturation pulse results in a second chemical displacement between the water and the fat in a second spatial saturation band that results in a final spatial saturation band being free of chemical shift displacement after application of the second saturation pulse, the second chemical shift displacement being different from the first chemical shift displacement.