Dual Visco Sealed-Up Technique for Ophthalmic Surgery

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Solution Overview

Problem

Current ophthalmic surgery methods, such as the soft shell technique, require skilled operators and are not suitable for glaucoma surgery due to potential postoperative complications like increased intraocular pressure and difficulty in completely eliminating viscoelastic substances, which can lead to bacterial endophthalmitis.

Innovation Solution

The Dual Visco Sealed-Up Technique involves injecting two viscoelastic substances with different surface tensions into specific areas of the anterior chamber in a specific order to ensure stable and uniform surgical procedures, using aqueous solutions containing hyaluronic acid or its salts, allowing for easy and effective sealing of incision sites and maintaining anterior chamber depth.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If the soft shell technique is used, then protective effects for corneal endothelium are improved, but intraocular pressure increases and viscoelastic substance elimination becomes difficult

Engineering Contradiction:
Improveprotective effects for corneal endotheliumVSAvoidintraocular pressure increase and postoperative complications
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent divides the viscoelastic substance injection into two distinct stages: first injecting a dispersion type viscoelastic substance for corneal endothelium protection, then injecting a polymer coagulation type viscoelastic substance for anterior chamber cavity maintenance. This segmentation allows each substance to perform its specific function optimally while enabling complete elimination of the first substance before the second is introduced, preventing the harmful accumulation of viscoelastic substances.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent requires complete elimination of the dispersion type viscoelastic substance before injecting the polymer coagulation type viscoelastic substance. This preliminary action ensures that the incision site is fully sealed by the first substance before the second substance is introduced, preventing leakage and allowing complete removal of the first substance without causing intraocular pressure increase or postoperative complications.

Inventive Principle:
Principle #10Preliminary action

2Ease of operation

If the soft shell technique is used, then operability is improved, but surgical quality becomes dependent on ophthalmologist skill level

Engineering Contradiction:
ImproveoperabilityVSAvoidsurgical quality consistency
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The patent segments the surgical procedure into two distinct injection stages with clear criteria for substance selection and injection timing. The first stage uses dispersion type viscoelastic substance for corneal endothelium protection, and the second stage uses polymer coagulation type viscoelastic substance for anterior chamber cavity maintenance. This segmentation provides a standardized protocol that can be consistently applied by ophthalmologists of varying skill levels, ensuring uniform surgical quality.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent specifies clear parameters for viscoelastic substance selection, including surface tension differences and injection timing requirements. By defining these parameters objectively, the patent creates a reproducible surgical protocol that reduces dependence on individual ophthalmologist skill levels and ensures consistent surgical quality across different practitioners.

Inventive Principle:
Principle #35Parameter changes

3Duration of action of stationary object

If viscoelastic substance is not completely eliminated, then cavity maintenance is improved, but postoperative bacterial endophthalmitis risk increases

Engineering Contradiction:
Improveanterior chamber cavity maintenanceVSAvoidpostoperative bacterial endophthalmitis risk
Core Design Contradiction:
Duration of action of stationary objectVSObject-generated harmful factors

Solution Approach 1:

The patent segments the viscoelastic substance injection into two stages, with the first dispersion type substance completely eliminated before the second polymer coagulation type substance is introduced. This segmentation ensures that the incision site is fully sealed by the first substance, allowing complete elimination without compromising cavity maintenance, thereby preventing postoperative bacterial endophthalmitis.

Inventive Principle:
Principle #1Segmentation

Solution Approach 2:

The patent requires complete elimination of the dispersion type viscoelastic substance before injecting the polymer coagulation type viscoelastic substance. This preliminary action ensures that no residual viscoelastic substance remains to serve as a medium for bacterial growth, while still maintaining proper anterior chamber cavity through the second substance's sealing action.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This method enables ophthalmologists of varying skill levels to perform surgeries with consistent quality and reduced risk of complications, including easier elimination of viscoelastic substances and prevention of postoperative issues like intraocular pressure elevation, making it suitable for glaucoma and cataract surgeries.

Implementation Method 1

injecting a first viscoelastic substance through an incision site which is lateral to cornea into an anterior chamber which is in an opposite part of the incision site with discharging aqueous humor

Methodology Applied
Scientific EffectViscoelasticity: Viscoelasticity

Implementation Method 2

injecting a second viscoelastic substance having higher surface tension than that of the first viscoelastic substance through the incision site into the remaining anterior chamber unfilled with the first substance

Methodology Applied
Scientific EffectSurface tension: Surface Tension

Implementation Method 3

injecting a third viscoelastic substance having lower surface tension than that of the second viscoelastic substance through the incision site into an area of the anterior chamber which is filled with the first viscoelastic substance until the incision site is sealed with the already injected the second viscoelastic substance

Methodology Applied
Scientific EffectSurface tension: Surface Tension

Data Source

PatentUS9539138B2Method of ophthalmic surgery and kit therefor
Publication Date: 2017.01.10 SEIKAGAKU KOGYO CO LTD
  • US9539138B2 patent drawing
  • US9539138B2 patent drawing

AI summary

A method of micro-incision ophthalmic surgery, comprising, in the order mentioned, the steps of:(1) injecting a first viscoelastic substance through an incision site which is lateral to corneal into an anterior chamber which is in an opposite part of the incision site with discharging aqueous humor;(2) injecting a second viscoelastic substance having higher surface tension than that of the first viscoelastic substance through the incision site into the remaining anterior chamber unfilled with the first viscoelastic substance; and(3) injecting a third viscoelastic substance having lower surface tension than that of the second viscoelastic substance through the incision site into an area of the anterior chamber which is filled with the first viscoelastic substance until the incision site is sealed with the already injected the second viscoelastic substance.