Deformation Vector Field Correction for Contour Propagation

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Solution Overview

Problem

In fractionated radiation therapy, manual and semi-automated contouring processes for tumor and critical structure delineation in IMRT are prone to errors and do not accurately account for changes over time, leading to potential misalignment of radiation beams and increased exposure to healthy tissues.

Innovation Solution

An automated method involving the computation of a deformation vector field (DVF) for spatial registration of planning and treatment images, with user correction capabilities that allow feedback to refine the DVF, ensuring accurate contour propagation and radiation therapy planning adjustments.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If automated contour propagation using non-rigid registration is employed, then productivity is improved, but manufacturing precision deteriorates due to errors in contour accuracy

Engineering Contradiction:
Improvecontour propagation efficiencyVSAvoidcontour accuracy
Core Design Contradiction:
ProductivityVSManufacturing precision

Solution Approach 1:

The system implements feedback by detecting contour errors through comparison with reference contours and correcting the deformation vector field (DVF) based on these errors. The correction process uses the detected errors to refine the DVF, which then improves the accuracy of contour propagation while maintaining automated efficiency.

Inventive Principle:
Principle #23Feedback

2Manufacturing precision

If manual contour correction is performed, then manufacturing precision is improved, but productivity deteriorates due to intensive manual work

Engineering Contradiction:
Improvecontour accuracyVSAvoidcontouring speed
Core Design Contradiction:
Manufacturing precisionVSProductivity

Solution Approach 1:

The system introduces an intermediary automated correction mechanism that acts as a mediator between manual contouring and final contour propagation. The correction system automatically detects errors and adjusts the DVF without requiring manual intervention for each correction, thereby maintaining high precision while improving productivity.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Adaptability or versatility

If non-rigid spatial registration is used for treatment images, then adaptability is improved to account for organ changes, but device complexity increases

Engineering Contradiction:
Improveaccommodation of anatomical changesVSAvoidregistration system complexity
Core Design Contradiction:
Adaptability or versatilityVSDevice complexity

Solution Approach 1:

The system changes parameters of the deformation vector field to adapt to anatomical variations between planning and treatment images. By adjusting DVF parameters based on detected contour errors, the system achieves adaptability to organ changes while managing complexity through automated parameter optimization rather than complex manual registration procedures.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentEP2751778B1Integration of user inputs and correction of deformation vector field in deformable image registration workflow
Publication Date: 2017.10.11 KONINKLIJKE PHILIPS NV
  • EP2751778B1 patent drawingFigure 1
  • EP2751778B1 patent drawingFigure 2
  • EP2751778B1 patent drawingFigure 3

AI summary

Adeformation vector field (DVF) (22)is computed that relatively spatially registers a first image (16)and a second image (14). A contour (26)delineating a structure in the first image is adapted using the DVF to generate an initial contour (52)for the structure in the second image. A final contour (56)is received for the structure in the second image. The DVF is corrected based on the initial and final contours for the structure in the second image to generate a corrected DVF (32).The correction may comprise computing an adjustment DVF (62)relating the initial and final contoursand combining the DVF and the adjustment DVF to generate the corrected DVF.The final contour may be received by displaying the second image overlaid with the initial contour, and receiving user adjustments of the overlaid contour withthe overlaid contour updated for each received user adjustment.