Diffusion-Weighted MRI Noise Reduction via Gradient Timing

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Solution Overview

Problem

Diffusion-weighted magnetic resonance (DWI) measurements are typically very loud due to the high demands on the gradient system, making them unpleasant for patients and sometimes causing refusal.

Innovation Solution

The method involves activating a diffusion module with diffusion gradients and an acquisition module that reads out measurement data by repetitions of RF excitation pulses, where the RF excitation pulse is applied only after the phase-encoding gradients have reached their required strength, significantly reducing noise levels.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If diffusion gradients are activated for diffusion encoding in DWI measurements, then diffusion weighting and diagnostic information are improved, but noise level increases making measurements unpleasant for patients

Engineering Contradiction:
Improvediffusion weightingVSAvoidnoise level
Core Design Contradiction:
Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The phase-encoding gradients are activated in advance before the RF excitation pulse is applied. This preliminary action ensures that the gradients reach their required strength before the measurement sequence begins, thereby reducing the noise generated during the actual diffusion-weighted imaging acquisition.

Inventive Principle:
Principle #10Preliminary action

2Measurement precision

If high strength diffusion gradients are used for diffusion encoding, then diffusion weighting capability is improved, but load on the gradient system increases

Engineering Contradiction:
Improvediffusion weighting capabilityVSAvoidload on gradient system
Core Design Contradiction:
Measurement precisionVSStress or pressure

Solution Approach 1:

The phase-encoding gradients are activated in advance before the RF excitation pulse, allowing the gradient system to reach the required strength beforehand. This distributes the load more efficiently and reduces peak demands on the gradient system during the actual measurement.

Inventive Principle:
Principle #10Preliminary action

3Manufacturing precision

If diffusion gradients are activated for spatial encoding, then image quality and diagnostic information are improved, but noise level increases causing patient discomfort

Engineering Contradiction:
Improveimage qualityVSAvoidnoise level
Core Design Contradiction:
Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

The phase-encoding gradients are activated in advance before the RF excitation pulse is applied. This ensures that the gradients reach their required strength before the measurement sequence begins, thereby reducing the noise generated during the actual diffusion-weighted imaging acquisition while maintaining image quality.

Inventive Principle:
Principle #10Preliminary action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach facilitates quiet DWI measurements by minimizing noise, allowing for the acquisition of diffusion data such as parameter maps, while reducing the load on the gradient unit and maintaining image quality.

Implementation Method 1

placing the subject under examination in a magnetic resonance scanner in a strong static, homogeneous basic magnetic field, also called the B0 field

Methodology Applied
Scientific EffectMagnetic field: Magnetic Field

Implementation Method 2

Radio frequency excitation pulses (RF pulses, also known as the B1 field) are applied to the subject under examination in order to induce nuclear spin resonances

Methodology Applied
Scientific EffectNuclear spin resonance:

Implementation Method 3

diffusion of water molecules along the applied diffusion gradients attenuates the measured magnetic resonance signal

Methodology Applied
Scientific EffectDiffusion: Diffusion

Implementation Method 4

Rapidly switched magnetic gradient fields are superimposed on the basic magnetic field for spatially encoding the measurement data

Methodology Applied
Scientific EffectMagnetic gradient: Magnetic Field

Data Source

PatentUS10459054B2Method and apparatus for implementing a diffusion-weighted magnetic resonance measurement
Publication Date: 2019.10.29 SIEMENS HEALTHINEERS AG
  • US10459054B2 patent drawing
  • US10459054B2 patent drawing
  • US10459054B2 patent drawing

AI summary

The method and magnetic resonance apparatus for acquiring diffusion-weighted measurement data from a subject, (a) a diffusion module is activated that contains at least one diffusion gradient, and (b) an acquisition module is activated, which reads out measurement data by repetitions of RF excitation pulses, which are applied to the subject under examination, and phase-encoding gradients that are activated to spatially encode signals induced by the RF pulses. For at least one repetition, the RF excitation pulse are applied to the subject only if the phase-encoding gradients, activated for the spatially encoding signals, which are generated after the RF excitation pulse, have already reached their required strength. Steps (a) and (b) are repeated until all the required measurement data are acquired. The acquired measurement data are stored. A significant reduction in the noise level of DWI measurements is thereby achieved.