Dynamic Imaging Mode Switching for Cell Culture Observation

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Solution Overview

Problem

Current observation systems for cultured cells lack the ability to efficiently switch between high-speed imaging for overview scans and high-resolution imaging, limiting their capability to monitor cell cultures effectively over time.

Innovation Solution

An observation apparatus with an imaging unit, driving mechanism, and control unit that switches between a high-speed mode for rough scans and a lower-speed, higher-resolution mode for detailed imaging, allowing for efficient monitoring of cell cultures by moving the imaging unit to change observation positions.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If the imaging unit moves at high speed to perform overview scans, then the scanning speed and productivity are improved, but the image resolution deteriorates

Engineering Contradiction:
Improvescanning speedVSAvoidimage resolution
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The system dynamically switches between two operational modes: a first mode for high-speed low-resolution imaging and a second mode for low-speed high-resolution imaging. The control unit automatically transitions between these modes based on real-time imaging requirements, allowing the imaging unit to adapt its speed and resolution characteristics dynamically rather than operating in a fixed state

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system changes key operational parameters including moving speed, image resolution, and imaging interval based on the imaging task. When performing overview scans, the imaging unit moves at high speed with lower resolution requirements; when detailed observation is needed, the system reduces speed and increases resolution, thereby optimizing parameters according to specific operational needs

Inventive Principle:
Principle #35Parameter changes

2Measurement precision

If the imaging unit moves at low speed to achieve high resolution, then the image resolution is improved, but the scanning speed and productivity deteriorate

Engineering Contradiction:
Improveimage resolutionVSAvoidscanning speed
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The system dynamically adjusts its operational state by switching between two modes. In the second mode, the imaging unit operates at low speed to capture high-resolution images when detailed observation is required, while the control unit manages the transition to maintain overall system efficiency

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system employs periodic switching between high-speed and low-speed modes based on imaging requirements. Rather than maintaining a constant speed, the imaging unit alternates between rapid overview passes and slower detailed imaging sequences, creating a periodic pattern that balances productivity and resolution needs

Inventive Principle:
Principle #19Periodic action

3Measurement precision

If the imaging unit remains stationary, then the image resolution is improved, but the ability to observe wide areas and multiple positions deteriorates

Engineering Contradiction:
Improveimage resolutionVSAvoidobservation area
Core Design Contradiction:
Measurement precisionVSArea of stationary object

Solution Approach 1:

The system makes the imaging unit dynamic by enabling it to move to different positions while maintaining the capability to capture high-resolution images at each position. The control unit coordinates movement with imaging operations, allowing the system to cover wide areas through multiple positioned observations rather than requiring a single stationary high-resolution view

Inventive Principle:
Principle #15Dynamics

Data Source

PatentUS10129474B2Observation apparatus, measurement system and observation method
Publication Date: 2018.11.13 OLYMPUS CORPORATION(JP)
  • US10129474B2 patent drawing
  • US10129474B2 patent drawing
  • US10129474B2 patent drawing

AI summary

An observation apparatus includes an imaging unit, a driving mechanism and a control unit. The imaging unit takes images of a target object. The driving mechanism moves the imaging unit to change an observation position of the target object. The control unit controls the driving mechanism and the imaging unit while switching between a first mode in which the imaging unit takes images while simultaneously being moved at a high speed by the driving mechanism, and a second mode in which the imaging unit takes images having a higher resolution than the images taken in the first mode while simultaneously being moved at a speed lower than that of the first mode.