Dynamic Magnification for Biological Specimen Observation
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Solution Overview
Problem
Conventional biological specimen observation apparatuses using time lapse observation cannot accurately observe regions where changes in biological specimens occur, as they maintain a fixed magnification rate for both change detection and observation, limiting high-magnification observation of changed areas.
Innovation Solution
The apparatus employs a dual-mode observation system for macro and micro observations, allowing adjustable magnification rates and prioritization of observation schedules to focus on changed regions, using a combination of macro and micro object lenses and image analysis to dynamically adjust observation parameters based on detected changes.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If a fixed magnification rate is used for both change detection and observation, then the observation system is simple to operate, but high-magnification observation of changed areas cannot be achieved
Solution Approach 1:
The system dynamically adjusts the magnification rate based on detected changes in the biological specimen. When a change is detected by the image analysis unit, the observation unit automatically switches to a higher magnification rate to observe the changed region in detail, transforming the fixed magnification system into an adaptive dynamic system that optimizes observation accuracy while maintaining ease of operation through automated control
Solution Approach 2:
The invention changes the magnification parameter from a fixed value to a variable that can be adjusted based on the observation needs. The system uses image analysis to detect changes and automatically modifies the magnification rate parameter, allowing the same observation system to operate at different magnification levels without requiring manual intervention, thus resolving the contradiction between operational simplicity and observation accuracy
2Device complexity
If the same magnification rate is maintained for change detection and detailed observation, then the observation schedule is easy to manage, but detailed observation of changed regions is limited
Solution Approach 1:
The observation process is segmented into two distinct phases: a first observation phase using a first magnification rate for change detection, and a second observation phase using a second magnification rate for detailed observation of changed regions. This segmentation allows each phase to use the appropriate magnification level, improving detection precision without significantly increasing system complexity since the same observation unit is used for both phases
Solution Approach 2:
The system performs preliminary observation at a lower magnification rate to detect changes before switching to high-magnification observation. This preliminary action allows the system to identify which regions require detailed observation, enabling efficient resource allocation and maintaining manageable system complexity while achieving high detection precision when needed
3Measurement precision
If high magnification is used for all observations, then detailed observation is achieved, but the observation area coverage is reduced
Solution Approach 1:
The system applies different magnification rates to different regions of the biological specimen based on local needs. Changed regions that require detailed observation are viewed at high magnification, while unchanged regions are monitored at low magnification. This local quality approach ensures that high observation detail is applied only where necessary, maintaining broad area coverage while achieving detailed observation of critical regions
Data Source
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AI summary
The present invention relates to a biological specimen observation apparatus whereby observation of a biological specimen can be performed accurately. In macro observation, a biological change region is extracted from a macro image (S32), a micro observation point corresponding to an extracted biological change region is registered (S33), and an object for tracking is identified. In micro observation, it is judged from the micro image whether or not biological change has continued in the biological change region at the micro observation point (S41), and the registered micro observation point is updated on the basis of this judgment result (S42). By this means, it is possible to carry out both macro observation for detecting a biological change region and micro observation for observing the progress of growth of a partial minute region where biological change has been exhibited, and therefore it is possible to carry out accurate observation of a biological specimen. The present invention can be applied to a biological specimen observation apparatus which carries out observation of a biological specimen, for example.