Dynamic PAP Control for Sleep-Wake State Detection

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Solution Overview

Problem

Conventional Positive Airway Pressure (PAP) systems for treating Obstructive Sleep Apnea Syndrome (OSAS) apply pressure unnecessarily during wakefulness, causing discomfort and interfering with breathing pattern analysis, as they do not differentiate between sleep and wake states effectively.

Innovation Solution

A system with sensors and a processing arrangement that analyzes breathing patterns to determine the sleep or wake state of a patient, adjusting the airway pressure accordingly, using a neural network to identify REM sleep, wakefulness, and sleep states, and controlling the pressure to maintain comfort and treat sleep disorders.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If PAP therapy applies pressure continuously during sleep and wakefulness, then airway collapse is prevented during sleep, but patient discomfort increases during wakefulness

Engineering Contradiction:
Improveairway collapse preventionVSAvoidpatient discomfort
Core Design Contradiction:
ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The system dynamically adjusts the level of PAP therapy based on detected sleep-wake state. During wakefulness, pressure is reduced to comfortable levels, while during sleep, pressure increases to therapeutic levels to prevent airway collapse. This dynamic adaptation resolves the contradiction by making the system responsive to changing physiological conditions.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system uses feedback from sleep-wake detection (via sensors monitoring physiological parameters) to automatically adjust pressure delivery. The detection system provides continuous information about patient state, and the control system responds by modulating pressure accordingly, ensuring therapeutic effectiveness during sleep while minimizing discomfort during wakefulness.

Inventive Principle:
Principle #23Feedback

2Reliability

If PAP therapy applies constant pressure, then airway patency is maintained during sleep, but breathing pattern analysis is interfered with

Engineering Contradiction:
Improveairway patencyVSAvoidbreathing pattern information
Core Design Contradiction:
ReliabilityVSLoss of information

Solution Approach 1:

The system transitions from constant pressure to dynamic pressure modulation based on sleep-wake state detection. By adjusting pressure levels according to patient state, the system maintains airway patency during sleep while allowing natural breathing patterns to emerge during wakefulness, thereby preserving breathing pattern information for analysis.

Inventive Principle:
Principle #15Dynamics

Solution Approach 2:

The system implements periodic assessment of patient state and相应 adjustment of pressure levels. This periodic modulation allows the system to maintain therapeutic pressure during sleep periods while reducing pressure during wakeful periods, enabling breathing pattern analysis without compromising airway patency during critical sleep phases.

Inventive Principle:
Principle #19Periodic action

Data Source

PatentUS12053580B2System and method for diagnosis and treatment of a breathing pattern of a patient
Publication Date: 2024.08.06 NEW YORK UNIV
  • US12053580B2 patent drawing
  • US12053580B2 patent drawing
  • US12053580B2 patent drawing

AI summary

Described is a system including a sensor and a processing arrangement. The sensor measures data corresponding to a patient's breathing patterns. The processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of a REM sleep state. In another embodiment, the processing arrangement analyzes the breathing patterns to determine whether the breathing patterns are indicative of one of the following states: (i) a wake state and (ii) a sleep state. In another embodiment, a neural network analyzes the data to determine whether the breathing patterns are indicative of one of the following states: (i) a REM sleep state, (ii) a wake state and (iii) a sleep state. In another embodiment, the processing arrangement analyzes the data to determine whether the breathing pattern is indicative of an arousal.