Dynamic Scanning Speed for Dry-Chemical Test Element Analysis
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Solution Overview
Problem
Existing dry-chemical test element analysis methods face challenges in accurately scanning assay regions with varying measurement light intensities, leading to inadequate signal detection due to either low sensitivity or detector overload, especially when analyte concentrations differ significantly.
Innovation Solution
Adapting scanning parameters, such as scanning speed and exposure time, based on the specific measurement light intensity of each assay region to ensure the detector operates within its working range, using a control device to adjust the quantity of light impinging on the detector and employing measures like optical filters and diaphragms to optimize light detection.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Measurement precision
If a constant scanning speed is used during optical scanning, then the scanning process is simple and fast, but regions with low measurement light intensity cannot be detected with sufficient sensitivity while regions with high intensity cause detector overload
Solution Approach 1:
The patent implements dynamic scanning speed adjustment based on the measured light intensity of each assay region. The control device automatically adapts the scanning speed to match the signal characteristics of each region, using slower speeds for low-intensity regions to improve detection sensitivity and faster speeds for high-intensity regions to prevent detector overload, thereby resolving the contradiction between measurement precision and device complexity
Solution Approach 2:
The patent changes the scanning parameter (scanning speed) dynamically according to the measurement conditions of each assay region. By adjusting the scanning speed parameter in response to varying light intensities, the system maintains optimal detection performance across regions with different analyte concentrations without requiring complex manual intervention
2Productivity
If a fixed exposure time is set for the detector device, then the scanning process is efficient and simple, but adequate signal detection cannot be achieved across assay regions with varying light intensities
Solution Approach 1:
The patent implements dynamic exposure time adjustment where the control device automatically adapts the detector exposure time based on the measured light intensity of each assay region. This dynamic adaptation maintains high scanning efficiency while ensuring adequate signal detection accuracy across regions with varying analyte concentrations, resolving the contradiction between productivity and measurement precision
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
This approach allows for precise and reliable analysis of dry-chemical test elements by ensuring the detector operates within its linear range, preventing saturation and non-linearities, and enabling accurate detection of both low and high analyte concentrations.
Implementation Method 1
measurement light beams which are produced in the scanned assay regions are detected by a detector device
Implementation Method 2
a fluorescent light produced in the respective assay region by means of the test light beams may be emitted with a different intensity
Data Source
AI summary
The invention relates to a method and an apparatus for analyzing a dry-chemical test element, in particular an immunological test element, wherein, in the method, a dry-chemical test element is analyzed by optical scanning, whereby measurement light beams leaving assay regions of the test element, which are loaded with one or more immobilized optically active substances, with a respective measurement light intensity are detected by a detector device. The method comprises the following steps: during the optical scanning of a first assay region, from which the measurement light beams leave with a first measurement light intensity, a first quantity of light from measurement light beams which impinges on the detector device and a working range of the detector device are adapted to one another by selecting scanning parameters according to a first set of scanning parameters, and during the optical scanning of a second assay region, from which the measurement light beams leave with a second measurement light intensity which differs from the first measurement light intensity, a second quantity of light from measurement light beams which impinges on the detector device and the working range of the detector device are adapted to one another by selecting scanning parameters according to a second set of scanning parameters which differs from the first set of scanning parameters.