Earwax Biomarker Self-Sampling Kit with Lateral Flow Biosensor

The patent combines sample extraction and biomarker measurement functions into a single integrated device. The extraction device includes a sampling tip that collects earwax samples and directly transfers them to measurement chambers containing biosensors, eliminating the need for separate laboratory analysis procedures and reducing overall device complexity while enabling rapid point-of-care testing.

The device performs multiple functions within a single system: it extracts earwax samples from the ear canal, prepares the sample for analysis, and measures multiple biomarkers simultaneously using an array of biosensors. This multi-functional approach reduces the need for multiple separate devices and simplifies the overall testing process.

The patent uses biosensors as intermediary elements that are integrated into the extraction device. These biosensors contain specific recognition elements (antibodies, enzymes, or aptamers) that selectively bind to target biomarkers in the earwax sample, enabling specific and accurate detection. The biosensors translate biochemical interactions into measurable signals, ensuring measurement precision while maintaining the simplicity of in situ testing.

The patent replaces complex mechanical laboratory analysis systems with biochemical sensing mechanisms. Instead of using traditional mechanical separation and analysis methods, the device uses biosensors that rely on specific molecular recognition and signal transduction mechanisms to detect biomarkers, enabling rapid and accurate measurements without complex mechanical processing.