ECG Age and Sex Estimation From Single-Lead Neural Analysis

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Solution Overview

Problem

Conventional ECG systems often require multiple electrodes and struggle to accurately estimate age and sex from limited ECG data, limiting their applicability and efficiency.

Innovation Solution

Utilizing machine-learning techniques, particularly deep neural networks, to process short intervals of ECG data from fewer than 12 leads, enabling precise age and sex estimation.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional ECG systems use multiple electrodes (12 leads), then measurement precision is improved, but device complexity increases

Engineering Contradiction:
Improveage and sex estimation accuracyVSAvoidnumber of electrodes
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts and utilizes only the most informative ECG leads (specifically lead II) for age and sex estimation, eliminating the need for all 12 conventional leads. This selective extraction maintains estimation accuracy while significantly reducing device complexity and electrode requirements

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent employs machine learning models that learn to replicate the diagnostic capabilities of full 12-lead ECG analysis using simplified single-lead or few-lead inputs. The neural network copies the complex pattern recognition functions without requiring the complex hardware setup

Inventive Principle:
Principle #26Copying

2Device complexity

If conventional ECG systems process limited ECG data, then device complexity is reduced, but measurement precision deteriorates

Engineering Contradiction:
ImproveECG data requirementsVSAvoidage and sex estimation accuracy
Core Design Contradiction:
Device complexityVSMeasurement precision

Solution Approach 1:

The patent replaces traditional signal processing methods with machine learning models that automatically learn optimal feature extraction from ECG data. This substitution enables accurate age and sex estimation from minimal ECG data without requiring complex manual feature engineering or extensive data processing

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent changes the approach from processing extensive ECG data with traditional algorithms to processing minimal ECG data with machine learning models. The model parameters are optimized to extract maximum information from limited inputs, achieving high precision with reduced data requirements

Inventive Principle:
Principle #35Parameter changes

3Productivity

If machine-learning models process short ECG intervals, then productivity is improved, but measurement precision may deteriorate

Engineering Contradiction:
Improveprocessing speedVSAvoidage and sex estimation accuracy
Core Design Contradiction:
ProductivityVSMeasurement precision

Solution Approach 1:

The patent performs preliminary training of machine learning models on extensive ECG datasets during development, enabling the models to capture comprehensive age and sex characteristics. Once trained, the models can quickly and accurately estimate age and sex from short ECG intervals without requiring lengthy processing times during actual use

Inventive Principle:
Principle #10Preliminary action

Data Source

PatentUS12539087B2ECG-based age and sex estimation
Publication Date: 2026.02.03 MAYO FOUNDATION FOR MEDICAL EDUCATION & RESEARCH
  • US12539087B2 patent drawing
  • US12539087B2 patent drawing
  • US12539087B2 patent drawing

AI summary

Systems, methods, devices, and other techniques for estimating the age and sex of a person through analysis of an electrocardiogram (ECG) recording for the person. Some aspects include recording an ECG of a person, processing data representing the ECG with an age-estimation neural network to generate an estimated age of the person, and outputting an indication of the estimated age of the person. Other aspects include processing the ECG with a sex prediction neural network to generate a predicted sex of the person and outputting an indication of the predicted sex of the person.