Precordial ECG Amplitude Correction for Intraindividual Variability

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Solution Overview

Problem

Current methods for clinical electrocardiography (ECG) face challenges in accurately measuring and comparing precordial ECG amplitudes over time due to intraindividual changes such as heart rotation and body mass index (BMI) variations, which affect the solid angle of the heart's contour seen from the thoracic surface, leading to inconsistencies in serial ECG analyses.

Innovation Solution

The method introduces percentage corrections for intraindividual precordial ECG amplitudes based on the solid angle theory, using BMI and the position of the transition zone on the horizontal ECG plane to standardize measurements, allowing for accurate comparison of serial ECG data by adjusting for changes in heart rotation and BMI.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If standard ECG measurement methods are used, then the measurement process is simple and cost-effective, but the measurement precision deteriorates due to intraindividual variability from heart rotation and BMI changes

Engineering Contradiction:
Improveprecordial ECG amplitude measurement precisionVSAvoidmeasurement and correction process complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent applies preliminary action by pre-calculating and storing correction factors based on BMI categories and transition zone positions before actual ECG measurements are taken. The correction tables are prepared in advance, allowing clinicians to simply look up and apply corrections without performing complex calculations during patient assessment, thus improving measurement precision while maintaining procedural simplicity

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent changes parameters by introducing BMI-based correction factors and transition zone position adjustments to the standard ECG measurement process. Instead of measuring raw amplitudes alone, the system modifies the measurement by applying correction percentages derived from BMI categories (e.g., underweight, normal, overweight, obese) and transition zone locations (e.g., V1-V2, V2-V3, etc.), thereby improving measurement precision through parameter transformation

Inventive Principle:
Principle #35Parameter changes

2Reliability

If serial ECG measurements are compared without correction, then the analysis process is straightforward, but the reliability deteriorates due to intraindividual variability over time

Engineering Contradiction:
Improveserial ECG analysis reliabilityVSAvoidtime for correction calculation and application
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The patent applies preliminary action by pre-computing correction factors based on BMI categories and transition zone positions, storing them in ready-to-use tables. This eliminates the need for time-consuming calculations during serial ECG comparisons, allowing clinicians to quickly apply corrections and maintain reliable longitudinal analysis without significant time investment

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The patent uses copying by creating standardized correction tables that can be replicated and applied across multiple serial ECG measurements. The correction factors are copied from pre-established tables based on BMI and transition zone position, ensuring consistent and reliable corrections across different time points without requiring recalculation, thus improving reliability while minimizing time loss

Inventive Principle:
Principle #26Copying

Data Source

PatentEP4255301B1Adjustment of long term intraindividual changes in precordial ECG amplitudes
Publication Date: 2024.08.28 BIOPOTENTIAL OY LTD
  • EP4255301B1 patent drawingFigure 1
  • EP4255301B1 patent drawingFigure 2
  • EP4255301B1 patent drawingFigure 3

AI summary

The present disclosure lies in the general field of clinical electrocardiography (ECG), more specifically in ECG methods comprising precordial ECG amplitude measurements. The present invention relates to methods of determining a subject's corrected precordial ECG amplitude from an ECG measurement, which corrections are based on intraindividual changes such as the rotation position of the heart on the horizontal plane, and/or changes in body mass index. The methods are thus useful for adjustment of intraindividual changes over time in precordial ECG amplitudes, such as between two ECG measurements. The present invention further relates to a device, an apparatus and a computer program product, and to uses of said device, apparatus and computer program product in a method of determining a subject's corrected precordial ECG amplitude from an ECG measurement, and for improving the accuracy of electrocardiographic methods depending on precordial ECG amplitude measurements. For example, the methods and the device, apparatus or product can be advantageously used in a method of diagnosing left ventricular hypertrophy and/or hypertension in a subject.