ECG-Based Cardiac Activation Area Determination

The patent introduces a computational model as an intermediary between the non-invasive ECG measurements and the cardiac activation area determination. The model incorporates anatomical information from image data and electrical properties to translate surface ECG signals into accurate subsurface activation locations, thereby maintaining patient safety while improving measurement precision through mathematical transformation and multi-parameter integration

The patent replaces the mechanical/invasive approach of directly inserting catheters into the heart with a non-invasive computational electrophysiology system. By substituting physical intervention with mathematical modeling and signal processing, the system achieves accurate cardiac activation area determination without compromising patient safety or requiring invasive procedures

The patent creates a virtual copy of the cardiac electrical system through computational modeling. By simulating the cardiac activation process and comparing modeled ECG signals with measured signals, the system determines the cardiac activation area with high precision without requiring physical catheter insertion, thereby eliminating invasive risks while maintaining measurement accuracy

The computational model serves as an intermediary that bridges non-invasive measurements and precise cardiac activation area determination. The model integrates anatomical structures, electrical properties, and ECG signals to accurately locate activation areas without direct physical contact with the heart, thus reducing patient risk while preserving measurement precision