Intracardiac ECG Depth Mapping via Far Field Signal Cancellation

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Solution Overview

Problem

Conventional cardiac mapping systems struggle to accurately isolate and visualize intracardiac ECG signals, particularly due to interference from far field signals and the inability to effectively analyze electrical activity at depths within myocardial tissue, limiting the precision of arrhythmia detection and treatment.

Innovation Solution

A system and method utilizing a mapping engine executed by processors to receive and analyze electrical activity from multiple electrodes, employing spatial electrode signal analysis, linear and non-linear combinations, and neural networks to identify and visualize electrical signals at specific depths within cardiac tissue, thereby reducing far field interference and enhancing signal resolution.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If conventional cardiac mapping is used to create a three-dimensional map of the heart, then the basic electrical activity can be visualized, but far field signals mask or interfere with local field signals within the electrical activity

Engineering Contradiction:

Improvesignal isolation accuracyVSAvoidfar field signal interference

Core Design Contradiction:

Measurement precisionVSObject-affected harmful factors

Solution Approach 1:

The patent segments the electrical activity signals into different spatial components (local field signals vs. far field signals) using multiple electrodes positioned at different locations. By dividing the signal analysis into spatially distinct components, the system can isolate and analyze local field signals while filtering out far field interference.

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

The patent applies local quality by using multiple electrodes with different spatial characteristics to detect signals. Each electrode provides localized electrical activity measurements, and the system processes these local measurements to reconstruct a comprehensive three-dimensional map while emphasizing local field signal quality over far field noise.

Inventive Principle:

Principle #3Local quality

2Productivity

If conventional computer processing operation is used to analyze electrical activity, then a three-dimensional map can be generated, but the processing operation assumes all far field signals are the same on all electrodes which reduces accuracy

Engineering Contradiction:

Improvemapping generation speedVSAvoidelectrical signal analysis accuracy

Core Design Contradiction:

ProductivityVSMeasurement precision

Solution Approach 1:

The patent changes the processing parameters by implementing sophisticated signal analysis algorithms that account for spatial variations in far field signals across different electrodes. Instead of assuming uniform far field signals, the system adjusts processing parameters to recognize and compensate for spatial differences, thereby improving measurement precision while maintaining productivity.

Inventive Principle:

Principle #35Parameter changes

3Quantity of substance

If intracardiac ECG is collected during cardiac ablation procedure, then electrical activity on the surface of intracardiac tissue can be reflected, but the ECG is two-dimensional and cannot visualize electrical conduction beneath the surface of the myocardial tissue

Engineering Contradiction:

ImproveECG signal dataVSAvoiddepth information of electrical conduction

Core Design Contradiction:

Quantity of substanceVSLoss of information

Solution Approach 1:

The patent transitions from two-dimensional surface ECG mapping to three-dimensional volumetric electrical activity mapping. By incorporating multiple electrodes positioned at different depths and spatial locations within the heart, the system adds a depth dimension to the ECG data, enabling visualization of electrical conduction both on the surface and beneath the myocardial tissue surface.

Inventive Principle:

Principle #17Another dimension (Dimensionality change)

Data Source

PatentEP4483801A1Intracardiac unipolar far field cancelation using multiple electrode catheters and methods for creating an ECG depth and radial lens

Publication Date: 2025.01.01 BIOSENSE WEBSTER (ISRAEL) LTD

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AI summary

Embodiments of methods and systems for determining electrocardiogram (ECG) depth of electrical activity. Electrical activity from a plurality of electrodes of a catheter is received; and within the electrical activity, an electrical signal originating from a depth within cardiac tissue is identified. In some embodiments, spatial electrode signal analysis of the electrical activity may be performed for each electrode of the plurality of electrodes. In some embodiments, a linear and/or non-linear combination of signal components within the electrical activity may be calculated. In some embodiments, a neural network may be provided with the electrical signals and may determine an estimated distance to the nearest activation for at least one of the plurality of electrodes. A visualization of the identified electrical signals at a specified depth within the cardiac tissue may be provided for display.