Eczema Skin Composition Using Isododecane for Cooling and Hydration

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Solution Overview

Problem

Existing treatments for eczema, such as lubricants, corticosteroids, and antibiotics, are inadequate in addressing the cosmetic acceptance, skin hydration, and sensory benefits, and often cause side effects or resistance issues.

Innovation Solution

Compositions comprising alpha hydroxy acid, volatile emollient, and processed oat ingredient, specifically lactic acid, isododecane, and oat extract, provide improved skin appearance, hydration, and cooling sensation for eczema-afflicted skin.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If traditional lubricants and corticosteroids are used to treat eczema, then skin hydration and anti-inflammatory effects are improved, but cosmetic acceptance and sensory benefits deteriorate

Engineering Contradiction:

Improvetreatment effectivenessVSAvoidcosmetic acceptance

Core Design Contradiction:

ReliabilityVSEase of operation

Solution Approach 1:

The patent combines multiple previously separate treatment approaches into a single unified composition. It merges the moisturizing function of lubricants, the anti-inflammatory action of corticosteroids, and the soothing properties of colloidal oatmeal into one integrated topical formulation that delivers all benefits simultaneously, thereby improving cosmetic acceptance while maintaining treatment effectiveness.

Inventive Principle:

Principle #5Merging (Combining)

Solution Approach 2:

The invention uses a composite formulation containing multiple active ingredients working together: lubricants for hydration, corticosteroids for inflammation control, and colloidal oatmeal for skin protection and soothing. This composite approach allows each ingredient to contribute its specific benefit while the combination provides synergistic effects that improve overall cosmetic acceptance and therapeutic outcome.

Inventive Principle:

Principle #40Composite materials

2Reliability

If corticosteroids are used for long-term treatment, then anti-inflammatory effects are improved, but side effects worsen

Engineering Contradiction:

Improveanti-inflammatory effectVSAvoidside effects

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent incorporates colloidal oatmeal and lubricants as preliminary protective and soothing agents that prepare the skin for corticosteroid treatment and reduce potential irritation. These ingredients are included in advance to mitigate the harmful effects of long-term corticosteroid use, such as skin thinning and irritation, while maintaining the necessary anti-inflammatory benefits.

Inventive Principle:

Principle #10Preliminary action

Solution Approach 2:

Colloidal oatmeal acts as an intermediary substance that modulates the interaction between corticosteroids and the skin. It provides a protective barrier that allows corticosteroids to exert their anti-inflammatory effect while reducing direct contact and potential damage to skin tissues, thereby minimizing side effects during long-term treatment.

Inventive Principle:

Principle #24Intermediary (Mediator)

3Reliability

If antibiotics are used to treat bacterial resistance, then infection control is improved, but bacterial resistance worsens

Engineering Contradiction:

Improveinfection controlVSAvoidbacterial resistance

Core Design Contradiction:

ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent converts the harmful effect of bacterial resistance into a benefit by using colloidal oatmeal, which has natural antimicrobial properties that work against bacteria without contributing to resistance. The oatmeal components create an environment that inhibits bacterial growth while selecting for beneficial skin flora, effectively controlling infection without the negative consequence of promoting bacterial resistance.

Inventive Principle:

Principle #22Blessing in disguise (Convert harm into benefit)

4Reliability

If traditional treatment ingredients are used, then therapeutic effects are improved, but gentleness on sensitive skin deteriorates

Engineering Contradiction:

Improvetherapeutic effectVSAvoidskin irritation

Core Design Contradiction:

ReliabilityVSObject-affected harmful factors

Solution Approach 1:

The patent modifies the parameters of traditional treatment ingredients by using corticosteroid esters with improved safety profiles and by optimizing the concentration and form of active ingredients. The corticosteroid esters provide equivalent anti-inflammatory effects with reduced irritation, and the lubricants are selected for their gentle, non-irritating properties, thereby maintaining therapeutic effectiveness while improving compatibility with sensitive eczema-prone skin.

Inventive Principle:

Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The compositions effectively improve the cosmetic appearance and hydration of eczema-affected skin while providing a gentle cooling sensation, addressing the limitations of traditional treatments.

Implementation Method 1

volatile emollient... provide improved skin appearance, hydration, and cooling sensation

Methodology Applied

Scientific EffectEvaporation: Evaporation

Implementation Method 2

alpha hydroxy acid... improve the cosmetic appearance of skin afflicted with eczema

Methodology Applied

Scientific EffectChemical exfoliation:

Implementation Method 3

processed oat ingredient... improve... hydration of eczema-affected skin

Methodology Applied

Scientific EffectAbsorption: Absorption (physical)

Data Source

PatentUS20260069552A1Methods of Providing a Cooling Sensation to Skin Afflicted with Eczema

Publication Date: 2026.03.12 KENVUE BRANDS LLC

AI summary

Provided are methods of providing a cooling sensation to skin afflicted with eczema, the methods comprising topically applying to skin afflicted with eczema a composition comprising isododecane.