Edge-On Semiconductor Crystal Imager for High Resolution PET

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Solution Overview

Problem

Conventional PET devices face challenges in achieving high spatial resolution and detection sensitivity due to the complexity and cost of manufacturing finely pixellated scintillation crystal arrays, with scintillation crystal sheet detectors suffering from low efficiency in stopping high-energy photons and requiring precise alignment of minute crystal elements with photodetector elements.

Innovation Solution

The use of semiconductor crystal detectors arranged edge-on with respect to incoming photons, such as Cadmium-Zinc-Telluride (CZT) crystals, which directly absorb photons to produce electric pulses for position determination, allowing for superior photon detection efficiency and energy resolution without the need for scintillation crystals, and employing a cross-strip or pixellated electrode configuration for 3-D event localization.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Measurement precision

If scintillation crystal arrays are made finely pixellated to achieve high spatial resolution, then measurement precision improves, but device complexity and manufacturing difficulty increase significantly

Engineering Contradiction:
Improvespatial resolutionVSAvoidmanufacturing complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The patent extracts and eliminates the scintillation crystal component from the detection system, replacing it with direct semiconductor photon detection. This removes the need for finely pixellated crystal arrays and their associated manufacturing complexities while maintaining high spatial resolution through direct electronic detection methods

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent replaces the mechanical/optical system of scintillation crystals converting photons to light and then to electrical signals with a direct semiconductor electronic detection system. This substitution eliminates the need for precise mechanical alignment of crystal elements with photodetectors while achieving comparable or superior measurement precision

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

2Measurement precision

If scintillation crystal sheets are made thin to reduce beam spread for better resolution, then measurement precision improves, but detection efficiency decreases due to low photon stopping power

Engineering Contradiction:
Improveposition resolutionVSAvoiddetection efficiency
Core Design Contradiction:
Measurement precisionVSReliability

Solution Approach 1:

The patent changes the fundamental detection parameter from optical signal generation (scintillation) to direct electrical signal generation (semiconductor detection). This parameter change enables thin detector designs to maintain high detection efficiency because semiconductor materials have superior photon absorption coefficients compared to scintillation materials, eliminating the trade-off between thickness and detection efficiency

Inventive Principle:
Principle #35Parameter changes

3Reliability

If crystal sheet thickness is increased to improve photon stopping efficiency, then detection efficiency improves, but spatial resolution deteriorates due to increased beam spread

Engineering Contradiction:
Improvedetection efficiencyVSAvoidspatial resolution
Core Design Contradiction:
ReliabilityVSMeasurement precision

Solution Approach 1:

The patent replaces the mechanical constraint of crystal thickness with an electronic solution in semiconductor detectors. The direct electronic detection mechanism allows for thin detector designs that maintain high detection efficiency without the beam spread issues that plague scintillation crystal systems, as electronic signals do not undergo optical scattering

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

4Reliability

If conventional scintillation crystal systems are used, then detection capability is achieved, but manufacturing cost and complexity increase due to precise alignment requirements

Engineering Contradiction:
Improvedetection capabilityVSAvoidmanufacturing simplicity
Core Design Contradiction:
ReliabilityVSEase of manufacture

Solution Approach 1:

The patent extracts and removes the scintillation crystal component entirely, replacing it with a monolithic semiconductor detector structure. This elimination of the two-component system (crystal + photodetector) and their precise alignment requirements dramatically simplifies manufacturing while maintaining full detection capability

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent merges the photon absorption and electrical signal generation functions into a single semiconductor detector component. This consolidation eliminates the need for separate scintillation crystals and photodetectors, removing alignment requirements and simplifying the manufacturing process while preserving detection functionality

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach significantly increases image counts, reduces random and scatter coincidence background, and enhances image data quantification and contrast resolution, while being cost-effective and simpler to manufacture than traditional scintillation crystal systems, with improved spatial and energy resolutions leading to a log order increase in molecular probe sensitivity.

Implementation Method 1

semiconductor crystal detectors arranged in an edge-on orientation with respect to emitted photons from a subject to directly detect the emitted photons

Methodology Applied
Scientific EffectPhotoelectric effect: Photoelectric Effect

Implementation Method 2

which directly absorb photons to produce electric pulses for position determination

Methodology Applied
Scientific EffectPhoton absorption: Absorption (EM radiation)

Data Source

PatentUS8063380B2Semiconductor crystal high resolution imager
Publication Date: 2011.11.22 RGT UNIV OF CALIFORNIA
  • US8063380B2 patent drawing
  • US8063380B2 patent drawing
  • US8063380B2 patent drawing

AI summary

A radiation imaging device (10). The radiation image device (10) comprises a subject radiation station (12) producing photon emissions (14), and at least one semiconductor crystal detector (16) arranged in an edge-on orientation with respect to the emitted photons (14) to directly receive the emitted photons (14) and produce a signal. The semiconductor crystal detector (16) comprises at least one anode and at least one cathode that produces the signal in response to the emitted photons (14).