Edit Guided Processing for Time-Lapse Image Analysis

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Solution Overview

Problem

Current time-lapse image analysis in bioscience is hindered by the complexity of manual or semi-automatic processing required for mask detection and object tracking, leading to inefficiencies and errors that accumulate over time, especially in high-volume data scenarios.

Innovation Solution

A computerized edit guided processing framework that assists in efficient mask and track editing, allowing users to improve processing recipes and parameters without image processing knowledge, and logs processing updates for archiving and future reference, using assisted editing tools and guided processing methods to enhance automatic detection and tracking accuracy.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If manual or semi-automatic processing is used for mask detection and object tracking, then processing flexibility and adaptability are maintained, but user effort and time consumption increase significantly

Engineering Contradiction:
Improveuser effortVSAvoidprocessing automation
Core Design Contradiction:
Ease of operationVSExtent of automation

Solution Approach 1:

The patent introduces an edit-guided processing framework that acts as an intermediary between manual editing and fully automatic processing. Users provide edit guidance (annotations, corrections, or preferences) which the system then uses to automatically generate processing results, reducing direct manual effort while maintaining adaptability through the guidance mechanism.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system performs self-service by automatically learning from user edits and improving its processing algorithms without requiring users to have image processing expertise. The framework uses edit guidance to self-adjust parameters and improve detection/tracking performance autonomously across the image sequence.

Inventive Principle:
Principle #25Self-service

2Reliability

If basic manual editing tools are used, then simplicity is maintained, but errors accumulate over time in time-lapse sequences

Engineering Contradiction:
Improveprocessing accuracyVSAvoidprocessing framework
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

The system performs preliminary actions by pre-processing the image sequence and pre-generating masks and tracks before user review. This allows errors to be detected and corrected systematically rather than accumulating, as the framework prepares all processing results in advance for efficient user validation and correction.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The edit-guided framework implements feedback mechanisms where user corrections and edits are fed back into the processing algorithm. The system learns from these corrections and adjusts its parameters accordingly, preventing error accumulation by continuously improving based on user feedback throughout the processing of the time-lapse sequence.

Inventive Principle:
Principle #23Feedback

3Reliability

If users review and correct mistakes in early frames, then tracking accuracy improves, but significant time is lost due to repeated corrections across all frames

Engineering Contradiction:
Improvetracking accuracyVSAvoidreview and correction time
Core Design Contradiction:
ReliabilityVSLoss of time

Solution Approach 1:

The system generates preliminary tracking results for all frames before user review, allowing users to make single corrections that automatically propagate forward. This preliminary generation approach prevents the need to repeatedly review and correct the same errors across multiple frames, as corrections are applied systematically to the entire sequence.

Inventive Principle:
Principle #10Preliminary action

Solution Approach 2:

The framework segments the correction process by allowing users to focus on specific problematic regions or frames rather than reviewing the entire sequence. The edit guidance can be applied selectively to particular areas, and the system automatically extends these corrections appropriately through the time-lapse sequence, reducing overall review time.

Inventive Principle:
Principle #1Segmentation

4Measurement precision

If automatic processing is used without user guidance, then productivity is high, but detection and tracking precision deteriorate due to lack of domain knowledge

Engineering Contradiction:
Improvedetection precisionVSAvoidprocessing efficiency
Core Design Contradiction:
Measurement precisionVSProductivity

Solution Approach 1:

The edit-guided framework serves as an intermediary that translates user domain knowledge into processing parameters without requiring users to understand image processing techniques. Users provide high-level guidance (edits, corrections, preferences) and the system automatically converts these into precise detection and tracking parameters, maintaining both precision and productivity.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The system automatically adjusts processing parameters based on user edit guidance without requiring users to manually configure technical parameters. The framework learns from edits and dynamically changes detection and tracking parameters to optimize precision while maintaining high processing efficiency through automated parameter optimization.

Inventive Principle:
Principle #35Parameter changes

Data Source

PatentUS9286681B2Edit guided processing method for time-lapse image analysis
Publication Date: 2016.03.15 LEICA MICROSYSTEMS CMS GMBH
  • US9286681B2 patent drawing
  • US9286681B2 patent drawing
  • US9286681B2 patent drawing

AI summary

A computerized mask edit guided processing method for time-lapse image analysis performs by a computer program an assisted mask editing on an input image sequence to generate mask edit data, and performs a mask edit guided processing using the image sequence and the mask edit data. A computerized track edit guided processing method for time-lapse image analysis performs by a computer program an assisted track editing on an input image sequence to generate track edit data, and performs a track edit guided processing using the image sequence and the track edit data. A computerized edit guided processing method for time-lapse image analysis performs by a computer program a combination of assisted mask editing and assisted track editing on an input image sequence to generate edit data, and performs a combination of mask edit guided processing and track edit guided processing using the image sequence and the edit data.